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Am J Rhinol Allergy. 2018 Jan 1;32(1):27-30. doi: 10.2500/ajra.2018.32.4489.
Oral allergy syndrome.
Muluk NB1, Cingi C2.
Author information
1
From the Department of Otorhinolaryngology, Medical Faculty, Kirikkale University, Kirikkale, Turkey.
2
Department of Otorhinolaryngology, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey.
Abstract
OBJECTIVES:
To review oral allergy syndrome (OAS).

METHODS:
We searched several medical literature data bases with the following key words: "oral allergy syndrome," "OAS," "pollen-food allergy syndrome," "PFAS," "allergy," "diagnosis," "treatment."

RESULTS:
Oral allergy syndrome (OAS), also called "pollen-food allergy syndrome," is a type of food allergy brought about by flavors, nuts, raw fruit, and vegetables. The most well-known symptoms are mouth and throat itching, which starts rapidly after a food is placed in the mouth, and that, as a rule, continues for just a couple of minutes after the food has been swallowed.

The frequency of OAS with pollen allergy has been reported as 5-8%; 1-2% of patients with OAS with pollen allergy show extreme responses, e.g., anaphylaxis.

Birch tree pollen, ragweed pollen, and grass pollen hypersensitivity cause the symptoms.

The diagnosis of OAS is confirmed by a positive history and positive skin-prick test result triggered by the food's fresh extract. Oral challenge result is normally positive with the raw food and negative with the similar cooked food.

• CONCLUSION:
  Patients with grass allergy may have a response to peaches, oranges, celery, tomatoes, and melons.
• Patients with ragweed allergy may show OAS symptoms with melon, cucumber, banana, and zucchini. Physicians should be aware of OAS and know the appropriate treatment.

PMID: 29336286