Myxedema madness and hallucinations
Type of Spiritual Experience
The thyroid disease caused him to become fat, depressed and anxious; the obesity caused sleep apnea and the resulting sleep apnea caused sleep deprivation from which he got his hallucinations
But, what caused the thyroid disease? We will never know.
A description of the experience
J Clin Sleep Med. 2012 Dec 15;8(6):717-8. doi: 10.5664/jcsm.2274. "Myxedema madness" associated with newly diagnosed hypothyroidism and obstructive sleep apnea. Neal JM, Yuhico RJ.
This is the case report of a 32-year-old obese male with a history of agitation, hallucinations, and delirium, recently diagnosed with primary hypothyroidism; he gave a several month history of fatigue with nocturnal snoring and frequent awakening.
Polysomnogram revealed severe OSA; initiation of CPAP and levothyroxine resulted in immediate improvement. The lack of a previous psychiatric history and acuteness of presentation was consistent with hypothyroid psychosis complicated by sleep deprivation cause by untreated OSA.
Primary hypothyroidism is a common disorder often associated with depression. It is rarely associated with psychosis and was first described as "myxoedematous madness" in 1949. It has not been previously reported to cause psychosis when associated with obstructive sleep apnea. This case illustrates the need for examination of potential multiple organic causes in a patient who presents with psychosis in the critical care setting.
The source of the experiencePubMed
Concepts, symbols and science items
Activities and commonsteps
Sleep deprivation, insomnia and mental exhaustion