Observations placeholder

Gabapentin and Neurontin

Identifier

005706

Type of Spiritual Experience

Hallucination

Number of hallucinations: 1867

Background

 

 

A description of the experience

Gabapentin  - brand names Fanatrex, Gabarone, Gralise, Neurontin , Nupentin. It is a GABA analogue. It was originally developed for the treatment of epilepsy, and the treatment of seizures. It is approved for treatment of focal seizures and partial and mixed seizure disorders however there is insufficient evidence for it use in generalized epilepsy. “There is little data to support its initial use over older anticonvulsant medication for any type of seizure disorder”. There seems to be conflicting evidence on the hallucinatory effects – the figures from the eHealthme site are high, but in the UK, the incidence seems lower.

Gabapentin is also used in the Treatment Protocol for methamphetamine, cocaine and alcohol addiction. It is administered at a dosage of 1200 mg taken at bedtime for 40–60 days. Though the combination of flumazenil infusions and gabapentin tablets is a licensed treatment, there is no prohibition against a physician prescribing gabapentin outside the Prometa protocol.

Lots of experiences on EROWID

Gabapentin is also used to treat neuropathic pain such as fibromyalgia and hot flashes [!] “There are, however, concerns regarding the quality of the trials conducted”. Furthermore it has been used for migraines and bipolar disorder and yet again “There are, however, concerns regarding the quality of the research on its use to treat these conditions”.

Neurontin is one of Pfizer's best-selling drugs, and was one of the 50 most-prescribed drugs in the United States in 2003. However, Pfizer has come under heavy criticism and serious litigation for its marketing of Neurontin, facing allegations that, behind the scenes, Parke-Davis marketed the drug for at least a dozen supposed uses for which the drug had not been FDA approved

It may be effective in reducing pain and spasticity in multiple sclerosis, tests for smoking cessation treatment have had mixed results

Gabapentin has limited usefulness in the treatment of anxiety disorders such as social anxiety disorder and obsessive-compulsive disorder, in treatment-resistant depression, and for insomnia”.

From Wikipedia
Numerous cases have been brought against the makers of Neurontin, with convictions arising not only for the illegal promotion of off-label uses. Much of the popular use of Neurontin among physicians stems from the widespread illicit marketing that Pfizer was convicted of, which was communicated via promotional messages through advisory boards, consultants’ meetings, and accredited continuing medical education events posing as independent third-party organizations, co-opting opinion leaders, educational enterprises and academia in their marketing campaign. The convictions for fraud set a new standard that goes beyond “scientific misconduct” and elevates the seriousness of the suppression of negative or unsupportive evidence as a form of fraud. As part of a case (CIVIL ACTION NO. 04-cv-10739-PBS) brought by Kaiser Foundation Health Plan against Pfizer, it was noted that "The general neuropathic pain indication cannot be granted for Neurontin based on the clinical trials in painful diabetic peripheral neuropathy (DPN) and postherpetic neuralgia (PHN)."

On Jan, 01, 2017   83,679 people reported to have side effects when taking Gabapentin.  Among them, 743 people (0.89%) have Hallucination

On Jan, 09, 2017   83,679 people reported to have side effects when taking Gabapentin.  Among them, 100 people (0.12%) have Hallucination, Auditory

On Feb, 01, 2017   83,679 people reported to have side effects when taking Gabapentin.  Among them, 9 people (0.01%) have Hallucination, Olfactory

On Jan, 13, 2017   83,679 people reported to have side effects when taking Gabapentin.  Among them, 4 people (0.0%) have Hallucination, Tactile

 

On Jan, 22, 2017   75,357 people reported to have side effects when taking Neurontin.  Among them, 801 people (1.06%) have Hallucination

On Jan, 18, 2017   75,357 people reported to have side effects when taking Neurontin.  Among them, 179 people (0.24%) have Hallucination, Auditory

On Jan, 31, 2017 75,357 people reported to have side effects when taking Neurontin. Among them, 14 people (0.02%) have Hallucination, Olfactory

On Jan, 06, 2017   75,357 people reported to have side effects when taking Neurontin.  Among them, 17 people (0.02%) have Hallucination, Tactile

 

 

Time on Neurontin when people have Hallucination  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Hallucination 33.71% 29.21% 7.87% 7.87% 13.48% 6.74% 1.12%

Age of people who have Hallucination when taking Neurontin  :

  0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Hallucination 0.00% 0.14% 1.29% 6.02% 13.75% 17.77% 22.78% 38.25%

Severity of Hallucination when taking Neurontin  :

  least moderate severe most severe
Hallucination 11.11% 55.56% 33.33% 0.00%

How people recovered from Hallucination  :

  while on the drug after off the drug not yet
Hallucination 0.00% 0.00% 100.00%

 

 On Dec, 26, 2015: 37,268 people reported to have side effects when taking Gabapentin. Among them, 870 people (2.33%) have Death.

On Jan, 7, 2016: 56,341 people reported to have side effects when taking Neurontin. Among them, 1,067 people (1.89%) have Death.

Time on Neurontin when people have Death  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Death 41.82% 32.73% 7.27% 9.09% 7.27% 1.82% 0.00%

Age of people who have Death when taking Neurontin  :

  0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Death 0.00% 0.00% 0.94% 2.70% 7.42% 17.27% 21.59% 50.07%

The source of the experience

eHealthme

Concepts, symbols and science items

Symbols

Science Items

Activities and commonsteps

Activities

Overloads

Epilepsy drugs
Fibromyalgia

Commonsteps

Hearing voices

References