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Dr Duke's list of Chemicals and their Biological Activities in: Menispermum canadense L. (Menispermaceae) -- Moonseed



Type of Spiritual Experience


A description of the experience

Chemicals and their Biological Activities in: Menispermum canadense L. (Menispermaceae) -- Moonseed



No activity reported.


No activity reported.


(+)-Inotropic MAB ; Abortifacient DUKE1992B ; Adrenolytic MAB ; Amebicide 200 ug/ml PAM EC83=100 ug/ml orl rat MAB ; Analgesic LRN-JUL91 ; Anesthetic LRN-JUL91 ; Antiacetylcholinesterase; Antiacne MAB ; Antiadrenergic KCH ; Antiaggregant; Antialzheimeran COX ; Antiamnesic MAB ; Antiangiogenic X15322253 ; Antiarrhythmic; Antiarthritic COX ; Antibacillus MIC=200 ug/ml PR14:303 ; Antibacterial 100 mg/4x/day LRN-JUL91 12.5-2,500 ug/ml PAM MIC=6-630 ug/ml PR14:303 ; Antibiotic PAM ; Anticancer; Anticariogenic MAB ; Antichlamydial PH2 ; Anticholecystitic 5-20 mg/3x/day/orl PAM ; Anticholera 150 mg/man/day MAR ; Anticirrhotic PAM ; Anticonjunctivitic 0.2% PAM ; Anticonvulsant 411 ; Antidiarrheic 100 mg/4x/day LRN-JUL91 ; Antidysenteric; Antiedemic MAB ; Antiendotoxic CAN ; Antienterotoxic PAM ; Antiesherichic; Antigiardial 10 mg/kg/day 414 ; Antiglaucomic AHP136 ; Antigonorrhea PJB1(3):231 ; Antihepatomic MAB ; Antihepatotic PMP25:62 ; Antiherpetic FEL ; Antihistaminic CAN ; Antiinflammatory; Antiischemic MAB ; Antileishmanic 10 ug/ml PR4(4):132 ; Antilipogenic IC63=10 uM MAB ; Antimalarial 0.14-0.36 ug/ml JE32:161 50 uM PR4(4):132 ; Antimitotic MAB ; Antimuscarinic CAN ; Antimyalgic FEL ; Antimycotic MAB ; Antineoplastic LRN-JUN87 ; Antinephritic PMP25:62 ; Antiperistaltic BRU ; Antipharyngitic PAM ; Antiphotooxidative JAF48:1058 ; Antiplasmodial IC50=0.14-0.36 ug/ml; Antipneumonic PAM ; Antipyretic 3 x aspirin; Antisalmonella PJB1(3):231 ; Antisecretory; Antiseptic 25 ug/ml; Antishigellic 12.5 ug/ml PAM ; Antispasmodic JBH ; Antispermigenic JE32:173 ; Antistaphylococcic PJB1(3):231 ; Antistrep PAM ; Antisyphilitic FEL ; Antitrachomic 0.2%; Antitrypanosomic 411 ; Antitubercular MIC=25 ug/ml; Antitumor (brain) IC91=150 ug/ml W&M ; Antiulcer; Antivaginitic KCH ; Antiviral KCH ; Astringent DUKE1992B ; Bilirubinolytic PH2 ; Calcium-Antagonist MAB ; Candidicide 414 ; Cardiodepressant KCH ; Cardiotonic; Carminative CAN ; Cholagogue AEHD1:99 ; Cholekinetic; Choleretic 411 ; Collyrium DUKE1992B ; COX-2-Inhibitor 100 ug/ml; Cyclooxygenase-Inhibitor DUKE1992B ; Cytotoxic JBH ; Digestive AHP137 ; Diuretic AHP137 ; Emetic AEHD1:101 ; Fungicide 12.5-150 ug/ml PAM ; Glaucomagenic AHP136 ; Hemostat DUKE1992B ; Hypocholesterolemic JE27:243 ; Hypoglycemic; Hypotensive; Immunostimulant; Lachrymatory MAB ; Larvicide 9 ppm JCE10:115 ; Leucocytogenic PH2 ; Lipase-Inhibitor MED ; Lipoxygenase-Inhibitor IC50=118 uM PM60:421 ; Mutagenic; Mycobactericide MIC=25-50 ug/ml PR14:303 ; Mydriatic MAB ; Myocardiodepressant DUKE1992B ; Myorelaxant AHP137 ; Pesticide DUKE1992B ; Phototoxic 9 ppm JCE10:115 ; Plasmodicide IC50=0.14-0.36 ug/ml POP:117 ; Prostaglandin-Synthesis-Inhibitor 25 mg/kg ivn rbt CHP12:526 ; Protisticide IC50=0.14-0.36 ug/ml POP:117 ; Respiradepressant MAR ; RNA-Depressant DUKE1992B ; RT-Inhibitor EMP5:222 ; Sedative; Stomachic PJB1(1) ; Topoisomerase-II-Inhibitor 2.5 uM PM61:414 ; Trichomonicide M29 ; Trypanocide; Uterocontractant; Uterotonic 411 ; Vagostimulant man AHP136 ; Vasoconstrictor 414 ; Vasodilator 2 mg/kg cat AHP136 ; Vermifuge PJB1(1) ; Vibriofuge LRN-JUL91


Analgesic JNP54:724 ; Anesthetic JBH ; Antiaggregant DUKE1992B ; Antiarrhythmic 4 mg/kg ivn hmn JNP54:724 ; Antidopaminergic JNP54:725 ; Antiinflammatory JNP54:724 ; Calcium-Antagonist ipr mus 50 mg/kg JNP54:724 K09728 ; CNS-Depressant DUKE1992B ; Curare JBH ; Cytotoxic 10 ppm DUKE1992B ; Dopamine-Receptor-Inhibitor PM56(2):143 ; Hepatotoxic 150 mg/kg 3 mos orl JNP54:724 ; Hypotensive ED=3-8 mg/kg DUKE1992B ; Myorelaxant DUKE1992B ; Uterorelaxant DUKE1992B


Myorelaxant DUKE1992B


No activity reported.

FAT Seed 160,000 ppm; DUKE1992A

No activity reported.


Antibacterial DUKE1992B ; Antineuromuscular ED50=10 mg/kg; Antispasmodic KCH ; CNS-Depressant KCH ; Curaroid <1% tubocurarine HDN ; Hypotensive; PAF-Inhibitor FT62:150 ; Paralytic HDN ; Pesticide DUKE1992B ; Toxic HDN ; Vasodilator KCH


No activity reported.


No activity reported.

PROTEIN Seed 131,000 ppm; DUKE1992A

No activity reported.


ACE-Inhibitor PM56(2):134 ; Analgesic JNP53(4):993 ; Antiaggregant JNP53:993 ; Antialopecic JNP54:731 ; Antianginal JNP54:729 ; Antiarrhythmic 5 mg/kg ivn gpg JNP54:729 ; Antidandruff JNP54:731 ; Antihistaminic PM56(2):145 ; Antiinflammatory ACM:411 ; Antiischemic 3-5 mg/kg ivn JNP54:729 ; Antimitotic DUKE1992B ; Antioxidant PM56:145 ; Antiphagocytotic JNP54:729 ; Antipyretic M11 ; Antiseptic DUKE1992B ; Antisilicotic ACM:411 ; Antitumor (Lung) DUKE1992B ; Bradycardic W&W ; Calcium-Antagonist JNP53:993 ; Circulatory-Stimulant PMP23:59 ; Hepatotoxic W&W ; Hypotensive 10-15 mg/kg ivn rats JNP54:729 ; Immunosuppressant JNP54:730 ; Membranomodulator JNP54:731 ; Mutagenic JNP54:731 ; Myorelaxant ACM:411 ; Vasodilator PM56(2):134


No activity reported.

The source of the experience

Dr Dukes plant database

Concepts, symbols and science items



Science Items

Activities and commonsteps






411: Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.

414: Jim Duke's personal files

ACM:411: Jim Duke's personal files

AEHD1:101: Jim Duke's personal files

AEHD1:99: Jim Duke's personal files

AHP136: Jim Duke's personal files

AHP137: Jim Duke's personal files

BRU: Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.

CAN: Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.

CHP12:526: Huang, C. G., Chu, Z. L., Yang, Z. M. 1991. Effect of Berberine on Synthesis of Platelet TXA2 and Plasma PGI2 in Rabbits. Chung-Kuo Yao Li Hsueh Pao, 12(6): 526-528.

COX: Jim Duke's personal files

DUKE1992A: Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.

EMP5:222: Jim Duke's personal files

FEL: Jim Duke's personal files

FT62:150: Jim Duke's personal files

HDN: Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.

JAF48:1058: Jim Duke's personal files

JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

JCE10:115: Jim Duke's personal files

JE27:243: Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.

JE32:161: Jim Duke's personal files

JE32:173: Jim Duke's personal files

JNP53(4):993: Jim Duke's personal files

JNP53:993: Jim Duke's personal files

JNP54:724: Jim Duke's personal files

JNP54:725: Jim Duke's personal files

JNP54:729: Jim Duke's personal files

JNP54:730: Jim Duke's personal files

JNP54:731: Jim Duke's personal files

K09728: Jim Duke's personal files

KCH: Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.

LRN-JUL91: Jim Duke's personal files

LRN-JUN87: Jim Duke's personal files

M11: Merck 11th Edition

M29: Martindale's 29th

MAB: Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.

MAR: Martindale's 28th

MED: Medline (post 1990 searches filed in my computer)

PAM: Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).

PH2: Jim Duke's personal files

PJB1(1): Jim Duke's personal files

PJB1(3):231: Jim Duke's personal files

PM56(2):134: Jim Duke's personal files

PM56(2):143: Jim Duke's personal files

PM56(2):145: Jim Duke's personal files

PM56:145: Jim Duke's personal files

PM60:421: Jim Duke's personal files

PM61:414: Kobayashi, Y, Yamashita, Y., Fujii, N., Takaboshi, K., Kawakami, T., Kawamura, M., Mizukami, T., Nakano, H. 1995. Inhibitors of DNA Topoisomerase I and II Isolated From the Coptis Rhizomes. Planta Medica, 61: 414-418.

PMP23:59: Jim Duke's personal files

PMP25:62: Jim Duke's personal files

POP:117: Jim Duke's personal files

PR14:303: Jim Duke's personal files

PR4(4):132: Jim Duke's personal files

W&M: Werbach & Murray, 1994.

W&W: Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)

X15322253: Jim Duke's personal files

ppm = parts per million
tr = trace


Mon Nov 2 11:10:51 EST 2015