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Dr Duke's list of Chemicals and their Biological Activities in: Menispermum canadense L. (Menispermaceae) -- Moonseed

Identifier

018369

Type of Spiritual Experience

Background

A description of the experience

Chemicals and their Biological Activities in: Menispermum canadense L. (Menispermaceae) -- Moonseed


Chemicals

ACUTIMIDINE Rhizome: DUKE1992A

No activity reported.

ACUTIMINE Rhizome: DUKE1992A

No activity reported.

BERBERINE Plant: DUKE1992A

(+)-Inotropic MAB ; Abortifacient DUKE1992B ; Adrenolytic MAB ; Amebicide 200 ug/ml PAM EC83=100 ug/ml orl rat MAB ; Analgesic LRN-JUL91 ; Anesthetic LRN-JUL91 ; Antiacetylcholinesterase; Antiacne MAB ; Antiadrenergic KCH ; Antiaggregant; Antialzheimeran COX ; Antiamnesic MAB ; Antiangiogenic X15322253 ; Antiarrhythmic; Antiarthritic COX ; Antibacillus MIC=200 ug/ml PR14:303 ; Antibacterial 100 mg/4x/day LRN-JUL91 12.5-2,500 ug/ml PAM MIC=6-630 ug/ml PR14:303 ; Antibiotic PAM ; Anticancer; Anticariogenic MAB ; Antichlamydial PH2 ; Anticholecystitic 5-20 mg/3x/day/orl PAM ; Anticholera 150 mg/man/day MAR ; Anticirrhotic PAM ; Anticonjunctivitic 0.2% PAM ; Anticonvulsant 411 ; Antidiarrheic 100 mg/4x/day LRN-JUL91 ; Antidysenteric; Antiedemic MAB ; Antiendotoxic CAN ; Antienterotoxic PAM ; Antiesherichic; Antigiardial 10 mg/kg/day 414 ; Antiglaucomic AHP136 ; Antigonorrhea PJB1(3):231 ; Antihepatomic MAB ; Antihepatotic PMP25:62 ; Antiherpetic FEL ; Antihistaminic CAN ; Antiinflammatory; Antiischemic MAB ; Antileishmanic 10 ug/ml PR4(4):132 ; Antilipogenic IC63=10 uM MAB ; Antimalarial 0.14-0.36 ug/ml JE32:161 50 uM PR4(4):132 ; Antimitotic MAB ; Antimuscarinic CAN ; Antimyalgic FEL ; Antimycotic MAB ; Antineoplastic LRN-JUN87 ; Antinephritic PMP25:62 ; Antiperistaltic BRU ; Antipharyngitic PAM ; Antiphotooxidative JAF48:1058 ; Antiplasmodial IC50=0.14-0.36 ug/ml; Antipneumonic PAM ; Antipyretic 3 x aspirin; Antisalmonella PJB1(3):231 ; Antisecretory; Antiseptic 25 ug/ml; Antishigellic 12.5 ug/ml PAM ; Antispasmodic JBH ; Antispermigenic JE32:173 ; Antistaphylococcic PJB1(3):231 ; Antistrep PAM ; Antisyphilitic FEL ; Antitrachomic 0.2%; Antitrypanosomic 411 ; Antitubercular MIC=25 ug/ml; Antitumor (brain) IC91=150 ug/ml W&M ; Antiulcer; Antivaginitic KCH ; Antiviral KCH ; Astringent DUKE1992B ; Bilirubinolytic PH2 ; Calcium-Antagonist MAB ; Candidicide 414 ; Cardiodepressant KCH ; Cardiotonic; Carminative CAN ; Cholagogue AEHD1:99 ; Cholekinetic; Choleretic 411 ; Collyrium DUKE1992B ; COX-2-Inhibitor 100 ug/ml; Cyclooxygenase-Inhibitor DUKE1992B ; Cytotoxic JBH ; Digestive AHP137 ; Diuretic AHP137 ; Emetic AEHD1:101 ; Fungicide 12.5-150 ug/ml PAM ; Glaucomagenic AHP136 ; Hemostat DUKE1992B ; Hypocholesterolemic JE27:243 ; Hypoglycemic; Hypotensive; Immunostimulant; Lachrymatory MAB ; Larvicide 9 ppm JCE10:115 ; Leucocytogenic PH2 ; Lipase-Inhibitor MED ; Lipoxygenase-Inhibitor IC50=118 uM PM60:421 ; Mutagenic; Mycobactericide MIC=25-50 ug/ml PR14:303 ; Mydriatic MAB ; Myocardiodepressant DUKE1992B ; Myorelaxant AHP137 ; Pesticide DUKE1992B ; Phototoxic 9 ppm JCE10:115 ; Plasmodicide IC50=0.14-0.36 ug/ml POP:117 ; Prostaglandin-Synthesis-Inhibitor 25 mg/kg ivn rbt CHP12:526 ; Protisticide IC50=0.14-0.36 ug/ml POP:117 ; Respiradepressant MAR ; RNA-Depressant DUKE1992B ; RT-Inhibitor EMP5:222 ; Sedative; Stomachic PJB1(1) ; Topoisomerase-II-Inhibitor 2.5 uM PM61:414 ; Trichomonicide M29 ; Trypanocide; Uterocontractant; Uterotonic 411 ; Vagostimulant man AHP136 ; Vasoconstrictor 414 ; Vasodilator 2 mg/kg cat AHP136 ; Vermifuge PJB1(1) ; Vibriofuge LRN-JUL91

DAURICINE Rhizome: DUKE1992A

Analgesic JNP54:724 ; Anesthetic JBH ; Antiaggregant DUKE1992B ; Antiarrhythmic 4 mg/kg ivn hmn JNP54:724 ; Antidopaminergic JNP54:725 ; Antiinflammatory JNP54:724 ; Calcium-Antagonist ipr mus 50 mg/kg JNP54:724 K09728 ; CNS-Depressant DUKE1992B ; Curare JBH ; Cytotoxic 10 ppm DUKE1992B ; Dopamine-Receptor-Inhibitor PM56(2):143 ; Hepatotoxic 150 mg/kg 3 mos orl JNP54:724 ; Hypotensive ED=3-8 mg/kg DUKE1992B ; Myorelaxant DUKE1992B ; Uterorelaxant DUKE1992B

DAURINOLINE Rhizome: DUKE1992A

Myorelaxant DUKE1992B

DEHYDROCHEILANTHIFOLIN Plant: DUKE1992A

No activity reported.

FAT Seed 160,000 ppm; DUKE1992A

No activity reported.

MAGNOFLORINE Plant: DUKE1992A

Antibacterial DUKE1992B ; Antineuromuscular ED50=10 mg/kg; Antispasmodic KCH ; CNS-Depressant KCH ; Curaroid <1% tubocurarine HDN ; Hypotensive; PAF-Inhibitor FT62:150 ; Paralytic HDN ; Pesticide DUKE1992B ; Toxic HDN ; Vasodilator KCH

N-DESMETHYLDAURICIN Plant: DUKE1992A

No activity reported.

N-METHYLINDCARPINMETHIODIDE Plant: DUKE1992A

No activity reported.

PROTEIN Seed 131,000 ppm; DUKE1992A

No activity reported.

TETRANDRINE Rhizome: DUKE1992A

ACE-Inhibitor PM56(2):134 ; Analgesic JNP53(4):993 ; Antiaggregant JNP53:993 ; Antialopecic JNP54:731 ; Antianginal JNP54:729 ; Antiarrhythmic 5 mg/kg ivn gpg JNP54:729 ; Antidandruff JNP54:731 ; Antihistaminic PM56(2):145 ; Antiinflammatory ACM:411 ; Antiischemic 3-5 mg/kg ivn JNP54:729 ; Antimitotic DUKE1992B ; Antioxidant PM56:145 ; Antiphagocytotic JNP54:729 ; Antipyretic M11 ; Antiseptic DUKE1992B ; Antisilicotic ACM:411 ; Antitumor (Lung) DUKE1992B ; Bradycardic W&W ; Calcium-Antagonist JNP53:993 ; Circulatory-Stimulant PMP23:59 ; Hepatotoxic W&W ; Hypotensive 10-15 mg/kg ivn rats JNP54:729 ; Immunosuppressant JNP54:730 ; Membranomodulator JNP54:731 ; Mutagenic JNP54:731 ; Myorelaxant ACM:411 ; Vasodilator PM56(2):134

VIBURNITOL Leaf: DUKE1992A

No activity reported.

The source of the experience

Dr Dukes plant database

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Activities

Suppressions

Moonseed

Commonsteps

References

411: Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.

414: Jim Duke's personal files

ACM:411: Jim Duke's personal files

AEHD1:101: Jim Duke's personal files

AEHD1:99: Jim Duke's personal files

AHP136: Jim Duke's personal files

AHP137: Jim Duke's personal files

BRU: Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.

CAN: Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.

CHP12:526: Huang, C. G., Chu, Z. L., Yang, Z. M. 1991. Effect of Berberine on Synthesis of Platelet TXA2 and Plasma PGI2 in Rabbits. Chung-Kuo Yao Li Hsueh Pao, 12(6): 526-528.

COX: Jim Duke's personal files

DUKE1992A: Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.

EMP5:222: Jim Duke's personal files

FEL: Jim Duke's personal files

FT62:150: Jim Duke's personal files

HDN: Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.

JAF48:1058: Jim Duke's personal files

JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

JCE10:115: Jim Duke's personal files

JE27:243: Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.

JE32:161: Jim Duke's personal files

JE32:173: Jim Duke's personal files

JNP53(4):993: Jim Duke's personal files

JNP53:993: Jim Duke's personal files

JNP54:724: Jim Duke's personal files

JNP54:725: Jim Duke's personal files

JNP54:729: Jim Duke's personal files

JNP54:730: Jim Duke's personal files

JNP54:731: Jim Duke's personal files

K09728: Jim Duke's personal files

KCH: Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.

LRN-JUL91: Jim Duke's personal files

LRN-JUN87: Jim Duke's personal files

M11: Merck 11th Edition

M29: Martindale's 29th

MAB: Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.

MAR: Martindale's 28th

MED: Medline (post 1990 searches filed in my computer)

PAM: Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).

PH2: Jim Duke's personal files

PJB1(1): Jim Duke's personal files

PJB1(3):231: Jim Duke's personal files

PM56(2):134: Jim Duke's personal files

PM56(2):143: Jim Duke's personal files

PM56(2):145: Jim Duke's personal files

PM56:145: Jim Duke's personal files

PM60:421: Jim Duke's personal files

PM61:414: Kobayashi, Y, Yamashita, Y., Fujii, N., Takaboshi, K., Kawakami, T., Kawamura, M., Mizukami, T., Nakano, H. 1995. Inhibitors of DNA Topoisomerase I and II Isolated From the Coptis Rhizomes. Planta Medica, 61: 414-418.

PMP23:59: Jim Duke's personal files

PMP25:62: Jim Duke's personal files

POP:117: Jim Duke's personal files

PR14:303: Jim Duke's personal files

PR4(4):132: Jim Duke's personal files

W&M: Werbach & Murray, 1994.

W&W: Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)

X15322253: Jim Duke's personal files

ppm = parts per million
tr = trace

 

Mon Nov 2 11:10:51 EST 2015