Observations placeholder

Dr Duke's list of Chemicals and their Biological Activities in: Abies alba MILLER (Pinaceae) -- Silver-Fir



Type of Spiritual Experience


A description of the experience

Chemicals and their Biological Activities in: Abies alba MILLER (Pinaceae) -- Silver-Fir


ABIETIC-ACID Resin, Exudate, Sap: DUKE1992A

Antifeedant 382 ; Protisticide DUKE1992B ; Schistosomicide JNP39:436

ABIETINOLIC-ACID Resin, Exudate, Sap: DUKE1992A

No activity reported.


No activity reported.


No activity reported.

ALPHA-FENCHENE Leaf 50 - 70 ppm DUKE1992A

No activity reported.


Antibacterial CWW ; Antistaphylococcic CWW ; Dermal JBH ; Emetic PJB1(1) ; FLavor FEMA 10-130 ARC ; Fungicide HH2 ; Insectiphile PEP ; Irritant JBH ; Laxative PJB1(1) ; Perfumery JBH ; Pesticide DUKE1992B

ALPHA-PINENE Plant 590 - 826 ppm BML Resin, Exudate, Sap: DUKE1992A

Allelochemic DUKE1992B ; Allergenic M&R523 ; Antiacne JAR12:99 ; Antibacterial; Antifeedant JAF45:3276 ; Antiflu EMP5:195 ; Antiinflammatory 500 mg/kg; Antipneumonic X16248573 ; Antiseptic X16248573 ; Antispasmodic; Antistaphylococcic X16248573 ; Antiviral EMP5:195 ; Cancer-Preventive 525 ; Coleoptophile DUKE1992B ; Expectorant MIK ; FLavor FEMA 15-150 ARC ; Herbicide IC50=30 uM TOX ; Insecticide 0.82 uM/fly JAF50:4576 ; Insectifuge 50 ppm; Insectiphile JSPR22:141 ; Irritant JBH ; P450-2B1-Inhibitor IC50=0.087 uM X9242356 ; Perfumery ARC ; Pesticide DUKE1992B ; Sedative LRN-JUN90 ; Spasmogenic; Tranquilizer LRN-JUN90 ; Transdermal X7199340


No activity reported.

BETA-FENCHENE Leaf 5 - 7 ppm DUKE1992A

No activity reported.

BETA-PHELLANDRENE Plant 32 - 46 ppm DUKE1992A

Expectorant JBH ; Fungicide HH2 ; Perfumery M11

BETA-PINENE Leaf 218 - 304 ppm DUKE1992A Resin, Exudate, Sap: DUKE1992A

Allergenic M&R618 ; Antiinflammatory FT63(1):3 ; Antiseptic LAF ; Antispasmodic; Candidicide LAF337 ; FLavor FEMA 15-600 ARC ; Herbicide TOX ; Insectifuge 382 ; Irritant ZEB ; Perfumery ARC ; Pesticide DUKE1992B ; Spasmogenic CAN ; Transdermal X10408241

BORNYLENE Leaf 1 - 2 ppm DUKE1992A

No activity reported.

CAMPHENE Leaf 528 - 738 ppm DUKE1992A

Allelopathic CWW ; Antilithic? JBH ; Antioxidant JA6(4):33 ; Expectorant HH2 ; FLavor FEMA 15-175 ARC ; Hypocholesterolemic? JBH ; Insectifuge 382 ; Pesticide DUKE1992B ; Spasmogenic FT59:465


No activity reported.


No activity reported.

DELTA-3-CARENE Leaf 2 - 4 ppm DUKE1992A Resin, Exudate, Sap: DUKE1992A

Allergenic? M&R184 ; Antibacterial RIE12:5 ; Antiinflammatory ipr IJO15(4):194 ; Dermatitigenic M&R520 ; FLavor FEMA ARC ; Insectifuge 382 ; Irritant PJB1(2):263 ; Pesticide DUKE1992B

EO Leaf 2,500 - 3,500 ppm DUKE1992A

No activity reported.

GAMMA-TERPINENE Leaf 8 - 10 ppm DUKE1992A

Acaricide X11124373 ; ACE-Inhibitor 100 ug/ml (weak activity) K26575 ; Aldose-Reductase-Inhibitor 100 ug/ml TYK1992:95 ; Antiacetylcholinesterase IC23=1.2 mM JAF45:677 ; Antifeedant HH3 ; Antioxidant JA6(4):33 ; FLavor FEMA 1-40 ARC ; Insectifuge HH3 ; Irritant ZEB ; Perfumery ARC ; Pesticide DUKE1992B


No activity reported.


No activity reported.


Antiacetylcholinesterase IC25=1.2 mM JAF45:677 IC27=164 ug/ml JAF46:3434

LAEVOPIMARIC-ACID Resin, Exudate, Sap: DUKE1992A

No activity reported.


No activity reported.

LIMONENE Leaf 855 - 1,197 ppm DUKE1992A Resin, Exudate, Sap: DUKE1992A

Acaricide LC100=8 uM JAF50:4586 ; AChE-Inhibitor 453 ; Allelochemic JAF45:3276 ; Allergenic 1/20th carene M&R521 ; Antiacetylcholinesterase IC22-26=1.2 mM JAF45:677 ; Antiadenomic ACT13:64 ; Antialzheimeran? 453 ; Antiasthmatic X15598576 ; Antibacterial RIE12:5 ; Anticancer AEM401:131 ; Antiesophagitic ACT13:64 ; Antifeedant JAF45:3276 ; Antiflu EMP5:195 ; Antiinflammatory X15598576 ; Antilithic M29:1064 ; Antilymphomic X15778119 ; Antimetastatic (Stomach) ACT13:64 ; Antimutagenic EMP6:235 ; Antiobesity X15862904 ; Antiseptic JAF44:2802 ; Antispasmodic ED50=0.197 mg/ml FT59:465 ; Antitumor; Antitumor (Breast) AEM401:131 ; Antitumor (Colon) ACT13:64 ; Antitumor (Pancreas) AEM401:131 ; Antitumor (Prostate) AEM401:131 ; Antitumor (Stomach) ACT13:64 ; Antiviral; Apoptotic X14998133 ; Bronchoprotectant X15598576 ; Cancer-Preventive 525 ; Candidistat JAF40:2330 ; Chemopreventive AEM401:131 ; Cholesterolytic X18072821 ; Detoxicant; Enterocontractant JAR4:22 ; Expectorant; FLavor PJB1(3):242 ; Fungiphilic JAF43:2283 ; Fungistat JAF40:2330 ; GST-Inducer X1438594 ; Herbicide IC50=45 uM TOX ; Histaminic X15862904 ; Immunomodulator X15778119 ; Insecticide 0.37 uM/fly; Insectifuge 382 ; Interleukin-6-Inhibitor X17867636 ; Irritant; Lipolytic X15862904 ; Myorelaxant 50 mg/kg X12587690 ; Nematicide IC=100 ug/ml NIG ; NO-Genic X15778119 ; Ornithine-Decarboxylase-Inhibitor ~750 mg/kg (diet) BO2 ; Ozone-Scavenger X15598576 ; P450-Inducer; Peristaltic X18072821 ; Pesticide DUKE1992B ; Photosensitizer RIN ; Sedative ED=1-32 mg/kg W&W ; Transdermal X7199340


Anticonvulsant CAN ; Antifatigue JAD ; Antioxidant ACM:489 ; Cancer-Preventive 525 ; CNS-Sedative CAN ; FLavor FEMA 5-250 ARC ; Fungistat 1,000 ARC ; Motor-Depressant BVC:162 ; Pesticide DUKE1992B ; Sedative BVC:162 ; Sweetener ARC

MYRCENE Leaf 25 - 35 ppm DUKE1992A

ACE-Inhibitor 100 ug/ml K26575 ; Aldose-Reductase-Inhibitor TYK1992:95 ; Allergenic M&R154 ; Analgesic EMM18:28 ; Antibacterial DUKE1992B ; Anticonvulsant X11085358 ; Antimutagenic EMM18:28 ; Antinitrosaminic X10606544 ; Antinociceptive 10-20 mg/kg ipr mus JPP42:877 20-40 mg/kg scu mus JPP42:877 ; Antioxidant JA6(4):33 ; Antispasmodic PM&T20:213.1986 ; Chemopreventive 525 ; FLavor FEMA 0.5-9 ARC ; Fungicide TOX ; Hypothermic X11085358 ; Insectifuge DUKE1992B ; Irritant ZEB ; Myorelaxant 100-200 mg/kg X12587690 ; P450-2B1-Inhibitor IC50=0.14 uM X9242356 ; Perfumery JBH ; Pesticide DUKE1992B

NEOABIETINIC-ACID Resin, Exudate, Sap: DUKE1992A

No activity reported.

P-CYMENE Leaf 25 - 35 ppm DUKE1992A

Analgesic MAR ; Antiacetylcholinesterase IC40=1.2 mM JAF45:677 ; Antibacillary X10826719 ; Antibacterial JE26:74 ; Antiflu DUKE1992B ; Antirheumatalgic MAR ; Antiviral DUKE1992B ; FLavor FEMA 12-250 ARC ; Fungicide TOX ; Herbicide IC50=50 uM TOX ; Insectifuge HH3 ; Irritant ZEB ; Laxative ZEB ; Pesticide DUKE1992B ; Sedative ZEB ; Trichomonicide LD100=50 ug/ml FT67:279

PALUSTRINIC-ACID Resin, Exudate, Sap: DUKE1992A

No activity reported.

SABINENE Leaf 5 - 7 ppm DUKE1992A

Antibacterial X14506036 ; Antihelicobacter X14506036 ; Antiseptic X14506036 ; Antiulcer X14506036 ; Perfumery ARC


Aldose-Reductase-Inhibitor 724.6 uM PR7:252 ; Analgesic; Antiarthritic MAD ; Antibacterial MAR ; Antidandruff ALH ; Antidermatotic DUKE1992B ; Antieczemic DUKE1992B ; Antiichthyosic M29 ; Antiinflammatory PHZ46:156 ; Antineuralgic MAD ; Antioncychomycotic M29 ; Antioxidant KCH ; Antiperiodic DUKE1992B ; Antipodagric DUKE1992B ; Antipsoriac DUKE1992B ; Antipyretic DUKE1992B ; Antirheumatic PJB1(2):285 ; Antiseborrheic DUKE1992B ; Antiseptic ALH ; Antitumor PCF:49 ; Antitympanitic M11 ; Cancer-Preventive 525 ; Comedolytic M29 ; COX-2-Inhibitor COX2000 ; Cyclooxygenase-Inhibitor PCF:49 ; Dermatitigenic JBH ; Fungicide MIC 1,000 ug/ml FFJ11:257 ; Hypoglycemic EMP6:158 ; Insectifuge EB48:111 ; Keratolytic JBH ; Pesticide DUKE1992B ; Thermogenic 130 ppm SCI237:1601 ; Tineacide M29 ; Ulcerogenic DUKE1992B

SANTENE Leaf 45 - 63 ppm DUKE1992A

No activity reported.

SUCCINIC-ACID Resin, Exudate, Sap: DUKE1992A

Additive FEMA 200-2,000 ARC ; Antifeedant CPB38:2862 ; Bruchiphobe 382 ; Cancer-Preventive 525 ; Dye M11 ; Perfumery M11 ; Pesticide DUKE1992B

TERPINOLENE Leaf 28 - 38 ppm DUKE1992A

Allelochemic JAF45:3276 ; Antifeedant JAF45:3276 ; Antinitrosaminic X10606544 ; Antioxidant X14664510 ; Deodorant JBH ; FLavor FEMA 15-60 ARC ; Fungicide TOX ; Perfumery ARC ; Pesticide DUKE1992B

TRICYCLENE Leaf 45 - 63 ppm DUKE1992A

No activity reported.

The source of the experience

Dr Dukes plant database

Concepts, symbols and science items



Science Items

Activities and commonsteps



Silver fir



382: Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.

453: Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.

525: Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.

ACM:489: Jim Duke's personal files

ACT13:64: Jim Duke's personal files

AEM401:131: Jim Duke's personal files

ALH: A.L.L. Hunting. Encyclopedia of Shampoo Ingredients. Micelle Press, Cranford NJ. 467 pp.

ARC: Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Note: Most ARC numerical data were in mg/dl. I know of no other plant where zinc is more prevalent than other minerals and protein. These data should be viewed as suspect.

BML: Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980. Note: Three annual compilations on essential oils. Percentages multiplied by 250-10,000 ppm and rounded to get fresh and dry weights.

BO2: Jim Duke's personal files

BVC:162: Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC

CAN: Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.

COX2000: Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.

CPB38:2862: Jim Duke's personal files

CWW: Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.

DUKE1992A: Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.

EB48:111: Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.

EMM18:28: Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991.

EMP5:195: Economic & Medicinal Plant Research, 5: 195.

EMP6:158: Economic & Medicinal Plant Research, 6: 158.

EMP6:235: Economic & Medicinal Plant Research, 6: 235.

FFJ11:257: Jim Duke's personal files

FT59:465: Fitoterapia No.59-1984.

FT63(1):3: Jim Duke's personal files

FT67:279: Jim Duke's personal files

HH2: Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.

HH3: Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.

IJO15(4):194: Internat. J. Oriental Med. 15(4): 194, 1990+

JA6(4):33: Jim Duke's personal files.

JAD: Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.

JAF40:2330: Jim Duke's personal files

JAF43:2283: J. Agric. Food Chem. 43: 2283.

JAF44:2802: Jim Duke's personal files

JAF45:3276: Jim Duke's personal files

JAF45:677: Jim Duke's personal files

JAF46:3434: Jim Duke's personal files

JAF50:4576: Jim Duke's personal files

JAF50:4586: Jim Duke's personal files

JAR12:99: Jim Duke's personal files

JAR4:22: J. Aromatherapy 4: 22.

JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

JE26:74: Jim Duke's personal files

JNP39:436: Jim Duke's personal files

JPP42:877: Rao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990.

JSPR22:141: J. Stored. Prod. Res., 22:141, 1986.

K26575: Jim Duke's personal files

KCH: Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.

LAF: Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.

LAF337: Jim Duke's personal files

LRN-JUN90: Lawrence Review of Natural Products, Jun-90.

M&R154: Jim Duke's personal files

M&R184: Jim Duke's personal files

M&R520: Jim Duke's personal files

M&R521: Jim Duke's personal files

M&R523: Jim Duke's personal files

M&R618: Jim Duke's personal files

M11: Merck 11th Edition

M29: Martindale's 29th

M29:1064: Jim Duke's personal files

MAD: Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.

MAR: Martindale's 28th

MIK: Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.

NIG: Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.

PCF:49: Jim Duke's personal files

PEP: Pakistan Encyclopedia Planta Medica. 1986.

PHZ46:156: Pharmazie, 46: 156, 1991.

PJB1(1): Jim Duke's personal files

PJB1(2):263: Jim Duke's personal files

PJB1(2):285: Jim Duke's personal files

PJB1(3):242: Jim Duke's personal files

PM&T20:213.1986: Jim Duke's personal files.

PR7:252: Toyomizu, M., Sugiyama, S., Jin, R. L., Nakatsu, T. 1993. Alpha-Glucosidase and Aldose Reductase Inhibitors: Constituents of Cashew, Anacardium occidentale, Nut Shell Liquids. Phytotherapy Research, 7(3): 252-254.

RIE12:5: Revista Itiliana Eppos, 12: 5, 1994.

RIN: Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.

SCI237:1601: Jim Duke's personal files

TOX: Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.

TYK1992:95: Okamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.

W&W: Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)

X10408241: Jim Duke's personal files

X10606544: Jim Duke's personal files

X10826719: Jim Duke's personal files

X11085358: Jim Duke's personal files

X11124373: Jim Duke's personal files

X12587690: Jim Duke's personal files

X1438594: Jim Duke's personal files

X14506036: Jim Duke's personal files

X14664510: Jim Duke's personal files

X14998133: Jim Duke's personal files

X15598576: Jim Duke's personal files

X15778119: Jim Duke's personal files

X15862904: Jim Duke's personal files

X16248573: Jim Duke's personal files

X17867636: Jim Duke's personal files

X18072821: Jim Duke's personal files

X7199340: Jim Duke's personal files

X9242356: Jim Duke's personal files

ZEB: Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.

ppm = parts per million
tr = trace