Observations placeholder
Diphenhydramine
Identifier
002100
Type of Spiritual Experience
Background
The number of hallucinations is shown in brackets. The figures come from the eHealthme website – see sources
A description of the experience
Diphenhydramine - Diphenhydramine hydrochloride abbreviated DPH, sometimes DHM . Trade names Benadryl Dimedrol, Daedalon. It is also found in the name-brand products Nytol, Unisom , Tylenol [already covered elsewhere], Midol and Advil , though some Unisom products contain doxylamine instead. It is available as an over-the-counter (OTC) or prescribed HCl injectable.
On Jan, 04, 2017 3,284 people reported to have side effects when taking Diphenhydramine Hydrochloride. Among them, 28 people (0.85%) have Hallucination
On Jan, 19, 2017 3,284 people reported to have side effects when taking Diphenhydramine Hydrochloride. Among them, 5 people (0.15%) have Hallucination, Auditory
On Jan, 05, 2017 692 people reported to have side effects when taking Advil Congestion Relief. Among them, 3 people (0.43%) have Hallucinations
n Jan, 19, 2017 123 people reported to have side effects when taking Advil Allergy Sinus. Among them, 1 person (0.81%) has Hallucinations
On Jan, 02, 2017 851 people reported to have side effects when taking Advil Cold And Sinus. Among them, 6 people (0.71%) have Hallucinations
On Dec, 29, 2016 3,981 people reported to have side effects when taking Advil Liqui-gels. Among them, 13 people (0.33%) have Hallucinations
On Jan, 04, 2017 1,438 people reported to have side effects when taking Midol. Among them, 2 people (0.14%) have Hallucination
On Dec, 28, 2016 1,032 people reported to have side effects when taking Unisom. Among them, 19 people (1.84%) have Hallucination
Diphenhydramine is a histamine H1receptor antagonist. Antagonism is achieved through blocking the effect of histamine more than blocking its production or release. Diphenhydramine inhibits most responses of smooth muscle to histamine and acts as a vasoconstrictor by inhibiting the vasodilator effects of histamine. The antagonism may also produce anticholinergic effects, antiemetic effects, and significant sedative side-effects.
It is mainly used to treat allergies. But, like most other first-generation antihistamines, the drug also has a powerful hypnotic effect, and for this reason is often used as a nonprescription sleep aid, a mild anxiolytic, a motion sickness treatment and even a treatment for the common cold . The drug also acts as an antiemetic. It has been used to provide local anaesthesia. Diphenhydramine has been shown to build tolerance against its sedation effectiveness very quickly
It has also been used for the treatment of ‘extrapyramidal side-effects’ of many antipsychotics, such as the tremors that haloperidol can cause. In addition, injectable diphenhydramine can be used for life-threatening reactions (anaphylaxis) to allergens such as bee stings, peanuts, or latex, instead of epinephrine.
Side effects due to the potent anticholinergic action include dry mouth and throat, increased heart rate, pupil dilation, urinary retention, constipation, and, at high doses, hallucinations or delirium. Further side-effects include motor impairment (ataxia), flushed skin, blurred vision at nearpoint owing to lack of accommodation, abnormal sensitivity to bright light, difficulty concentrating, short-term memory loss, visual disturbances, irregular breathing, dizziness, irritability, itchy skin, confusion, decreased body temperature (in general, in the hands and/or feet), erectile dysfunction, excitability, and, although it can be used to treat nausea, higher doses may cause vomiting.
Some side-effects, such as twitching, may be delayed until the drowsiness begins to cease and the person is in more of an awakening mode. Considerable overdosage can lead to cardiac arrest, serious ventricular dysrhythmias, coma, and death.
Death of a child from topical diphenhydramine. - Turner JW; Department of Pathology, St. Louis University School of Medicine, St. Louis, Missouri 63104, USA.
Diphenhydramine is a drug readily available over the counter in the form of capsules, tablets, and syrup used for allergy relief. A topical form is sold as a cream without a prescription to alleviate itching. Diphenhydramine is a drug commonly found in postmortem toxicology reports. In rare instances, death is attributed to ingestion of lethal concentrations of the drug. Herein is a report of a toddler who died of lethal concentrations of diphenhydramine from topical application
.