Cisapride and Propulsid
Type of Spiritual Experience
A description of the experience
Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract. It acts directly as a serotonin 5-HT4 receptor agonist and indirectly as a parasympathomimetic. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. It has been sold under the trade names Prepulsid (Janssen-Ortho) and Propulsid (in the United States).
In many countries, it has been either withdrawn from the market or had its indications limited because of side-effects.
Cisapride has also been used for the treatment of gastroesophageal reflux disease (GERD).
In many countries, it has been either withdrawn or had its indications limited because of reports of the side-effect long QT syndrome, which may cause arrhythmias. The U.S. Food and Drug Administration (FDA) issued a warning letter to doctors, and cisapride was voluntarily removed from the U.S. market on July 14, 2000. Its use in Europe has also been limited. It was banned in India and in the Philippines in 2011
On Aug, 4, 2015: 7,936 people reported to have side effects when taking Propulsid. Among them, 34 people (0.43%) have Hallucination.
Gender of people who have Hallucination when taking Propulsid :
On Jan, 14, 2017 8,004 people reported to have side effects when taking Propulsid.
Among them, 150 people (1.87%) have Death