Berries, diabetes, cholesterol and the heart
Type of Spiritual Experience
A description of the experience
J Agric Food Chem. 2011 Nov 29. Strawberries, Blueberries, and Cranberries in the Metabolic Syndrome: Clinical Perspectives. Basu A, Lyons TJ. Nutritional Sciences, 301 Human Sciences, Oklahoma State University , Stillwater, Oklahoma 74078-6141, United States.
Emerging science supports therapeutic roles of strawberries, blueberries, and cranberries in metabolic syndrome, a prediabetic state characterized by several cardiovascular risk factors.
Interventional studies reported by our group and others have demonstrated the following effects: strawberries lowering total and LDL-cholesterol, but not triglycerides, and decreasing surrogate biomarkers of atherosclerosis (malondialdehyde and adhesion molecules); blueberries lowering systolic and diastolic blood pressure and lipid oxidation and improving insulin resistance; and low-calorie cranberry juice selectively decreasing biomarkers of lipid oxidation (oxidized LDL) and inflammation (adhesion molecules) in metabolic syndrome.
Mechanistic studies further explain these observations as up-regulation of endothelial nitric oxide synthase activity, reduction in renal oxidative damage, and inhibition of the activity of carbohydrate digestive enzymes or angiotensin-converting enzyme by these berries. These findings need confirmation in future studies with a focus on the effects of strawberry, blueberry, or cranberry intervention in clinical biomarkers and molecular mechanisms underlying the metabolic syndrome.
The source of the experiencePubMed
Concepts, symbols and science items
Activities and commonsteps
Heart failure and coronary heart disease