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Antifungal Activity of Apple Cider Vinegar on Candida Species Involved in Denture Stomatitis
Identifier
027490
Type of Spiritual Experience
Background
Denture stomatitis is caused by a yeast or fungus called candida. It is not an infection that we get or pass on to others, because we all have some candida in our mouths. Thrush can appear in other parts of the body, but when it affects the mouth it may be called ‘denture stomatitis'.
Denture stomatitis is caused by a yeast or fungus called candida. It is not an infection that we get or pass on to others, because we all have some candida in our mouths. Thrush can appear in other parts of the body, but when it affects the mouth it may be called ‘denture stomatitis'.
- Denture wearers are most likely to be affected, along with people who have problems keeping their mouth clean.
- Diabetics and anyone who takes steroids, either through inhalers or by mouth, may also have problems.
- Some antibiotics are responsible for causing thrush. Many people find that taking certain antibiotics encourages the infection to come back, especially if taken over a long period of time.
How can the dentist recognise it? When the denture is taken out, your dental team may be able to see a very red area under the denture. There may also be red sore areas at the corner of the lips.
If untreated, the condition can cause soreness in the mouth and may lead to poorly fitting dentures in the future.
A description of the experience
J Prosthodont. 2015 Jun;24(4):296-302. doi: 10.1111/jopr.12207. Epub 2014 Sep 14.
Antifungal Activity of Apple Cider Vinegar on Candida Species Involved in Denture Stomatitis.
Mota AC1, de Castro RD1, de Araújo Oliveira J1, de Oliveira Lima E1.
Author information
Abstract
PURPOSE:
To evaluate the in vitro antifungal activity of apple cider vinegar on Candida spp. involved in denture stomatitis.
MATERIAL AND METHODS:
The microdilution technique was used to determine the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of apple cider vinegar containing 4% maleic acid, and nystatin (control). Further tests of microbial kinetics and inhibition of adherence to acrylic resin were performed testing different concentrations (MIC, MICx2, MICx4) of the products at time intervals of 0, 30, 60, 120 and 180 minutes. A roughness meter was used to measure the changes in surface roughness; color change of the acrylic resin specimens exposed to the test products in different concentrations and time intervals were also evaluated.
RESULTS:
Apple cider vinegar (4%) showed MIC of 2500 μg/ml and MFC of 2500, 5000, and 10,000 μg/ml depending on the strain tested. Nystatin showed MIC of 3.125 μg/ml and strain-dependent MFC values ranging from 3.125 to 12.5 μg/ml. The microbial kinetic assay showed a statistical difference between apple cider vinegar and nystatin (p < 0.0001). After 30 minutes of exposure, apple cider vinegar showed fungicidal effect at MICx4, whereas nystatin maintained its fungistatic effect. Apple cider vinegar showed greater inhibition of adherence (p < 0.001) compared to control. Apple cider vinegar did not significantly alter the surface roughness of the acrylic resin specimens compared to nystatin (p > 0.05), and both had no influence on their color.
CONCLUSION:
Apple cider vinegar showed antifungal properties against Candida spp., thus representing a possible therapeutic alternative for patients with denture stomatitis.
© 2014 by the American College of Prosthodontists.
KEYWORDS:
Candida albicans; Dental prosthesis; acetic acid; denture stomatitis
PMID:
25219289
DOI:
10.1111/jopr.12207