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Observations placeholder

Fosamax hallucinations

Identifier

006845

Type of Spiritual Experience

Hallucination

Number of hallucinations: 432

Background

The number of hallucinations is shown in brackets and comes from the ehealthme web site

A description of the experience

On Dec, 12, 2015: 69,911 people reported to have side effects when taking Fosamax. Among them, 383 people (0.55%) have Hallucination.

On Dec, 20, 2016 5,837 people reported to have side effects when taking Alendronic Acid.  Among them, 49 people (0.84%) have Hallucinations

Alendronic acid or alendronate sodium  sold as Fosamax

 — is a bisphosphonate drug used for osteoporosis and several other bone diseases. It is marketed alone as well as in combination with vitamin D

As with all potent bisphosphonates, the systemic bioavailability after oral dosing is low, averaging only 0.6–0.7% in women and in men under fasting conditions. Intake together with meals and beverages other than water further reduces the bioavailability.

After absorption in the bone, alendronate has an estimated terminal half-life of 10 years.

Side-effects

The link can be followed for details of side effects, it covers 66,718 reports from FDA and social media of adverse reactions

  • Gastrointestinal tract: ulceration of the esophagus; this may require hospitalization and intensive treatment. Gastric and duodenal ulceration may also occur. December 31, 2008, the FDA reported alendronate and related drugs may carry an increased risk for esophageal cancer.
  • General: infrequent cases of skin rash, and toxic epidermal necrolysis, eye problems (uveitis, scleritis) and generalized muscle, joint, and bone pain. In laboratory tests decreased calcium and phosphate values may be obtained.
  • Osteonecrosis of the Jaw - Deterioration of the Temporomandibular Joint (TMJ) may occur while on this drug, if dental work of any kind is carried out.
  • Auditory hallucinations and visual disturbances have been associated with alendronate and other bisphosphonates.
  • Bone: Alendronate has been linked in long-term users to the development of low-impact femoral fractures. Further, studies suggest that users of alendronate have an increase in the numbers of osteoclasts and develop giant, more multinucleated osteoclasts; the significance of this development is unclear. People who have taken Fosamax has been linked to a rare type of leg fracture that cuts straight across the upper thigh bone after little or no trauma. Studies are showing that people who have taken Fosamax for more than five years are at risk for developing these kind of fractures. In some cases, patients have reported that, after weeks or months of unexplained aching, their thigh bones simply snapped while they were walking or standing. One doctor reports that a 59-year old previously healthy woman visiting New York City was riding a subway train one morning when the train jolted. She shifted all her weight to one leg, felt a bone snap, and fell to the floor of the train. An x-ray in a local emergency room revealed a comminuted spiral fracture involving the upper half of the right femur. She had been taking Fosamax for 7 years. On Oct. 13, 2010 the Food and Drug Administration issued a warning about these fractures

 On Dec, 5, 2015: 69,910 people reported to have side effects when taking Fosamax. Among them, 1,749 people (2.50%) have Death.

 

 

 

The source of the experience

eHealthme

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Commonsteps

References