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Uncontrollably Long High - Lamotrigine & Spice and Synthetic Cannabinoids by John EROWID

Daily Use: 100 mg Lamotrigine as an antidepressant [sic] 

I decided I'd go hang out with friends and smoke some herbal incense and have a good time for my birthday. We smoked two bowls of 'Da Shit' brand herbal incense. Here's the trip report for that experience: All times are approximate.

T0:00 Outdoors at picnic table. Smoked one bowl of herbal incense, taking big hits, can barely hold smoke in.
T0:05 Felt that 'am I getting high yet' feeling. Smoke another bowl.
T0:07 Body high sets in, the mid-sections of my limbs start to feel shaky and rubbery, then tingly.
T0:10 'Whoa!' moment, feels as though I tipped backwards off a boat and hit the water back-first. Total dry-mouth.
T0:30-2:30 Internal monologue is present but not exactly audible. Time stretching and short term memory loss sets in and Closed eye visual hallucinations including clouds changing directions instantaneously, pins and needles body-high, total clarity inside my head that doesn't translate very well in speech and behavior. I have to keep moving around to find comfortable positions. My kidneys feel like they're very warm. Any time I talk, I hear how ridiculous my words sound in comparison to my thoughts and try to acknowledge it to my companions (who are far less high than me), but get caught up in the laughing fits before I can finish my thoughts. My short term memory falters, and my vision shutters ….. I'm ready to get out.
T3:00 Fall asleep ……………………

T 12:00 (next morning) …. As part of my morning routine, I ingest 100mg of lamotrigine orally. A bit surprised at how long the high has lasted. My friends are completely sober. At this point, I believed I was just placebo-ing, but as the day goes on, I get more and more freaked out that I can't stop feeling stoned. ………………
Throughout the next few days, I continue to slip in and out of grogginess and numbness in my body and I am extremely anxious that I have fucked something up terribly and permanantly in my brain. Called my doctor who said the synthetic cannabinoid and lamotrigine reacted badly and that I would have to wait about 5 days to feel better.

This was attributed to the fact that JWH cannabinoids and lamotrigine are both sodium ion channel blockers, and have an analgesic (painkilling) effect [note that this is incorrect]. Now that I feel safe in knowing I'm not permanently fucked up, I can enjoy the ride. It was saturday afternoon when I last smoked and it is now tuesday afternoon and I have 36-72 hours left of being high to contend with.

Legal notice: At the time of the submission of this article, the possession and use of herbal incense blends containing non-structually-similar synthetic cannabinoids was not regulated in the city and state that they were purchased or used in.  Lamotrigine on the other hand is legal