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Observations placeholder

Allopurinol

Identifier

005117

Type of Spiritual Experience

Hallucination

Number of hallucinations: 594

Background

A description of the experience

Allopurinol  - trade names include Allohexal, Allosig, Milurit, Alloril, Progout, Zyloprim, Zyloric, Zyrik and Aluron,  is a drug used primarily to treat hyperuricemia (excess uric acid in blood plasma) and its complications, including chronic gout.

Allopurinol does not alleviate acute attacks of gout, but is useful in chronic gout to prevent future attacks.  It is also used as prophylaxis with chemotherapeutic treatments, which can rapidly produce severe hyperuricemia. Other established indications for allopurinol therapy include kidney stones with a uric acid component and kidney failure.

Allopurinol is an inhibitor of the enzyme xanthine oxidase. It is rapidly metabolized by its target, xanthine oxidase, to its active metabolite oxypurinol, which is also an inhibitor of xanthine oxidase. Allopurinol is almost completely metabolized to oxypurinol within two hours of oral administration, whereas oxypurinol is slowly excreted by the kidneys over 18-30 hours. For this reason, oxypurinol is believed to be responsible for the majority of allopurinol's effect.

 The most serious adverse effect is a hypersensitivity syndrome consisting of fever, skin rash, eosinophilia, hepatitis, worsened renal function, and, in some cases, allopurinol hypersensitivity syndrome.  But it is not this side effect that produces the hallucinations.

 On Jan, 21, 2017 76,218 people reported to have side effects when taking Allopurinol.  Among them, 367 people (0.48%) have Hallucination

On Jan, 27, 2017 76,218 people reported to have side effects when taking Allopurinol.  Among them, 58 people (0.08%) have Hallucination, Auditory

On Jan, 29, 2017   76,218 people reported to have side effects when taking Allopurinol.   Among them, 4 people (0.01%) have Hallucination, Tactile

On Jan, 26, 2017   76,218 people reported to have side effects when taking Allopurinol.  Among them, 129 people (0.17%) have Hallucination, Visual

On Jan, 29, 2017 76,218 people reported to have side effects when taking Allopurinol.
Among them, 36 people (0.05%) have Hallucinations, Mixed

 

Time on Allopurinol when people have Hallucination  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Hallucination 66.67% 11.11% 11.11% 11.11% 0.00% 0.00% 0.00%

Gender of people who have Hallucination when taking Allopurinol  :

  Female Male
Hallucination 32.48% 67.52%

Age of people who have Hallucination when taking Allopurinol  :

  0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Hallucination 0.00% 0.00% 0.35% 0.00% 2.80% 7.34% 11.89% 77.62%

Severity of Hallucination when taking Allopurinol  :

  least moderate severe most severe
Hallucination 0.00% 66.67% 33.33% 0.00%

The source of the experience

eHealthme

Concepts, symbols and science items

Symbols

Science Items

Activities and commonsteps

Activities

Overloads

Gout drugs

Commonsteps

Hearing voices

References