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Observations placeholder

Prolia, Denosumab and Xgeva

Identifier

024133

Type of Spiritual Experience

Hallucination

Number of hallucinations: 39

Background

A description of the experience

Denosumab (trade names Prolia and Xgeva) is a human monoclonal antibody for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone.

The most common side effects are joint and muscle pain in the arms or legs. Denosumab is contraindicated in people with low blood calcium levels. Denosumab is a RANKL inhibitor, which works by preventing the development of osteoclasts which are cells that break down bone. It was developed by the biotechnology company Amgen.

Most common Prolia side effects from eHealthme

  • Death - (5,610 reports)
  • Back pain - (2,320 reports)
  • Joint pain - (2,319 reports)
  • Pain in extremity - (2,308 reports)
  • Rashes - (1,944 reports)
  • Pain - (1,897 reports)
  • Osteonecrosis of jaw - (1,373 reports)
  • Muscle aches - (1,260 reports)
  • Weakness - (1,225 reports)
  • Bone pain - (1,092 reports)

Most common Xgeva side effects from eHealthme

  • Death - (2,102 reports)
  • Osteonecrosis of jaw - (1,767 reports)
  • Hypocalcaemia - (762 reports)
  • Fatigue - (637 reports)
  • Hospitalisation - (499 reports)
  • Nausea - (396 reports)
  • Weakness - (361 reports)
  • Breathing difficulty - (357 reports)
  • Diarrhea - (349 reports)
  • Pain - (336 reports)

On Jan, 28, 2017  34,310 people reported to have side effects when taking Prolia.  Among them, 26 people (0.08%) have Hallucination

On Feb, 14, 2017  34,310 people reported to have side effects when taking Prolia.  Among them, 7 people (0.02%) have Hallucination, Auditory

 

On Jan, 24, 2017  11,014 people reported to have side effects when taking Xgeva.  Among them, 6 people (0.05%) have Hallucination

 

The source of the experience

eHealthme

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Activities

Overloads

Osteoporosis treatments

Commonsteps

Hearing voices

References