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Ibuprofen is a medication in the nonsteroidal anti-inflammatory drug (NSAID) class that is used for treating pain, fever, and inflammation.  Ibuprofen was discovered in 1961 by Stewart Adams and marketed as Brufen. It is available under a number of trade names, including Advil and Motrin.

This includes painful menstrual periods, migraines, and rheumatoid arthritis. . It may also be used to close a patent ductus arteriosus in a premature baby. It can be used by mouth or intravenously. It typically begins working within an hour.

Common side effects include heartburn and a rash. Compared to other NSAIDs it may have fewer side effects such as gastrointestinal bleeding. It increases the risk of heart failure, kidney failure, and liver failure. At low doses, it does not appear to increase the risk of myocardial infarction [sic]; however, at higher doses it may. Ibuprofen can also result in worsened asthma. While it is unclear if it is safe in early pregnancy, it appears to be harmful in later pregnancy and therefore is not recommended. Like other NSAIDs, it works by inhibiting the making of prostaglandins by decreasing the activity of the enzyme cyclooxygenase. Ibuprofen might be a weaker anti-inflammatory than other NSAIDs.

Most common Motrin side effects from eHealthme

• Pain - (2,222 reports)
• Nausea - (1,779 reports)
• Drug ineffective - (1,655 reports)
• Stress and anxiety - (1,593 reports)
• Fatigue - (1,311 reports)
• Headache - (1,296 reports)
• Breathing difficulty - (1,253 reports)
• Nausea and vomiting - (1,235 reports)
• Chest pain - (1,181 reports)
• Fever - (1,177 reports)

On Jan, 28, 2017  23,082 people reported to have side effects when taking Motrin.
Among them, 296 people (1.28%) have Death

On Jan, 31, 2017  23,082 people reported to have side effects when taking Motrin.  Among them, 196 people (0.85%) have Hallucination

On Jan, 29, 2017  23,082 people reported to have side effects when taking Motrin. Among them, 81 people (0.35%) have Hallucination, Auditory