Observations placeholder
Dimenhydrinate
Identifier
002098
Type of Spiritual Experience
Background
A description of the experience
Dimenhydrinate
Dimenhydrinate is marketed under brand names Dramamine , Driminate, Gravol , Gravamin, Vomex, Viabom, Dramin, Anautin, Daedelon, Triptone, Dimetabs, Dinate and Vertirosan . It is an over-the-counter drug used to prevent nausea and motion sickness.
On Jan, 19, 2017 1,204 people reported to have side effects when taking Dimenhydrinate. Among them, 7 people (0.58%) have Hallucinations
On Dec, 22, 2016 384 people reported to have side effects when taking Dramamine. Among them, 4 people (1.04%) have Hallucination
On Jan, 02, 2017 991 people reported to have side effects when taking Gravol. Among them, 5 people (0.5%) have Hallucination
Chemically, dimenhydrinate is a salt of two drugs:
- Diphenhydramine
- and 8-chlorotheophylline - a chlorinated derivative of theophylline.
Diphenhydramine is found in a number of over the counter sleep aids and allergy preparations, such as Tylenol PM and Benadryl – see other entries. 8-chlorotheophylline is a stimulant drug of the xanthine chemical class. Like other xanthine derivatives, theophylline is both:
- A competitive nonselective phosphodiesterase inhibitor, which raises intracellular cAMP, activates PKA, inhibits TNF-alph and inhibits leukotriene synthesis, and reduces inflammation and innate immunity. There is more detail on the Leukotriene effects in the section Pharamaceuticals asthma and allergy treatments
- nonselective adenosine receptor antagonist,antagonizing A1, A2, and A3 receptors almost equally. More details of the adenoside efefcts are given in the section on Adenoside receptors
In other words, whatever effects are experienced with this drug are caused by the combination and are likely to be rather complex being a combination of adenoside activity, leukotriene activity and ant-histamine activity.
In terms of the number of experiences caused by involuntary use, the figure is low, but it is a drug that is used quite extensively ‘recreationally’
see EROWID LINK
Slang terms for Dramamine used this way include "dime," "dime tabs," "D-Q," "substance D," "d-house," and "drams." In the CNS, dimenhydrinate readily crosses the blood-brain barrier, exerting effects within the visual and auditory cortex. Users experience auditory/visual hallucinations coupled with short-term memory loss - though auditory hallucinations are more common than visual hallucinations, the visuals of a "Dramamine Trip" can seem very real. At higher doses the hallucinations are more frequent, realistic and in some cases, frightening. Users may see frightening creatures (such as insects or zombies), and to have conversations with non-existent people.