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Dr Duke’s list of Chemicals and their Biological Activities in: Senna alata (L.) ROXB. (Fabaceae) -- Ringworm Bush
Identifier
021419
Type of Spiritual Experience
Background
A description of the experience
Dr Duke’s list of Chemicals and their Biological Activities in: Senna alata (L.) ROXB. (Fabaceae) -- Ringworm Bush
Chemicals
1,3,8-TRIHYDROXY-2-METHYL-ANTHRAQUINONE Root: DUKE1992A
No activity reported.
1,5-DIHYDROXY-8-METHOXY-2-METHYL-ANTHRAQUINONE...GLUCOPYRANOSIDE Plant: DUKE1992A
No activity reported.
ALOE-EMODIN Plant: DUKE1992A
Antibacterial MIC=2-64 ug/ml; Antiherpetic AAC35:2463 ; Antileukemic; Antisalmonella CAN ; Antiseptic X10478467 ; Antistaphylococcic X10478467 ; Antitumor 1 ug/ml; Antiviral; Arylamine-N-Acetyltransferase-Inhibitor PH2 ; Calcium-Antagonist (strong activity); Candidicide MIC=25-250 ug/ml X10967452 ; Cathartic M11 ; Cytotoxic 20 ppm DUKE1992B ; Estrogenic X18563353 ; Fungicide MIC=25-250 ug/ml X10967452 ; Genotoxic JBH ; Laxative AEH113 ; Mutagenic AEH113 ; Pesticide DUKE1992B ; Purgative ED50=>59.6 mg/kg orl mus IJO16:195 ; Termitifuge JBH ; Topoisomerase-II-Inhibitor 1 mM MR371:165 IC50=741 uM/ml BBA1428:406 ; Tuberculostatic PEP
BETA-SITOSTEROL Root: DUKE1992A
Androgenic DUKE1992B ; Angiogenic X11988857 ; Anorexic MAR ; Antiadenomic M11 ; Antiandrogenic JE28:221 ; Antibacterial QJC28:155 ; Anticancer (Breast) PS131:95 ; Anticancer (Cervix) PJB1(2):287 ; Anticancer (Lung) PJB1(2):287 ; Antiedemic IC54=320 mg/kg orl DFN:160 ; Antiestrogenic JE28:221 ; Antifeedant 382 ; Antifertility JE28:221 ; Antigonadotrophic JE28:221 ; Antihyperlipoproteinaemic JBH ; Antiinflammatory; Antileukemic PJB1(2):287 ; Antilymphomic PJB1(2):287 ; Antimutagenic 250 ug/ml JAFC37:1365 ; Antiophidic 2.3 mg mus EMP5:363 ; Antioxidant IC44=10 uM JMF5:1 ; Antiprogestational JE28:221 ; Antiprostaglandin 30 mg/day/12 wks FT68(4):291 ; Antiprostatadenomic M11 ; Antiprostatitic 10-20 mg 3 x/day/orl man; Antipyretic HDN ; Antitumor (Breast) PS131:95 ; Antitumor (Cervix) PJB1(2):287 ; Antitumor (Lung) PJB1(2):287 ; Antiviral PS75:161 ; Apoptotic X17350814 ; Artemicide LC50=110 ppm PC29(5):1667 ; Cancer-Preventive 525 ; Candidicide QJC28:155 ; Caspase-8-Inducer X17358014 ; Estrogenic PHM9:52 ; Febrifuge HDN ; Gonadotrophic JE28:221 ; Hepatoprotective PMP23:60 ; Hypocholesterolemic 2-6 g/man/day/orl M30 9-3,330 mg/man/day/orl MAR ; Hypoglycemic JE27:243 ; Hypolipidemic 2-6 g/day; Pesticide DUKE1992B ; Spermicide JE28:221 ; Ubiquiot JBH ; Ulcerogenic 500 mg/kg ipr rat FT63(1):3
CHRYSAROBIN Leaf: DUKE1992A
Allergenic M11 ; Antipsoriac M29 ; Antitrichophytotic DUKE1992B ; Cytotoxic 1 ug/ml AEH ; Emetic DUKE1992B ; Fungicide M11 ; Irritant DUKE1992B ; Keratolytic DUKE1992B ; Mutagenic AEH ; Pesticide DUKE1992B
CHRYSOPHANOL Plant: DUKE1992A
Antibacterial QJC28:155 ; Antiseptic DUKE1992B ; Calcium-Antagonist 5/6 aloeemodin LAB107 ; Candidicide QJC28:155 ; Cathartic DUKE1992B ; Hemostat DUKE1992B ; Pesticide DUKE1992B ; Pigment JBH ; Purgative ED50=>500 mg/kg orl mus IJO16:195 ; Termitifuge JBH
CHRYSOPHANOL-GLYCOSIDE Leaf: DUKE1992A
No activity reported.
DIHYDROXYMETHYLANTHRAQUINONE Leaf: DUKE1992A
No activity reported.
EMODIN Plant: DUKE1992A
AGEs-Inhibitor IC50=118 uM X17978503 ; Aldose-Reductase-Inhibitor IC50=15.9 uM X17978503 ; Allergenic CAN ; Antiaggregant JNP33(3):630 ; Antiangiogenic; Antibacterial BOI ; Anticytomegalovirus ED50=1.1 ug/ml HG40:23 ; Antifeedant 382 ; Antiinflammatory 15 mg/kg IJE29:230 ; Antileukemic JBH ; Antilymphomic JNM7:51 ; AntiMRSA MIC 2-64 ug/ml X10478467 ; Antimutagenic FVT29:765 ; Antineoplastic JNM7:51 ; Antiplaque ED50=1.1 ug/ml HG40:23 ; Antiproliferant IC50=20-30 uM BO2 ; Antisarcomic PJB1(1):174 ; Antiseptic DUKE1992B ; Antispasmodic 411 ; Antisprout PJB1(1):174 ; Antitumor (Breast) IJO16:197 ; Antiulcer 15 mg/kg IJE29:230 ; Antivaginitic AKT ; Antiviral EC50=1.1 PM56(6):651 ED50=1.1 ug/ml HG40:23 ; Cathartic M11 ; CNS-Depressant 15 mg/kg ipr mus FT65(4):275 ; Collagenase-Inhibitor IC50=40 uM BO2 ; COX-2-Inhibitor; Cytotoxic CD50=2.6 ug/ml DUKE1992B ; Differentiator IC50=20-30 uM BO2 ; Estrogenic X18563353 ; Genotoxic AEH113 ; Gonadotropic JE26:82 ; Hypolipidemic BOI ; Immunostimulant BOI ; Immunosuppressant EJP198:211 ; iNOS-Inhibitor X12391547 ; Leucocytogenic BOI ; MMP-2-Inhibitor X19291397 ; MMP-7-Inhibitor X19291397 ; MMP-9-Inhibitor X19291397 ; Mutagenic AEH114 ; NO-Inhibitor IC50=60.7 uM X12391547 ; Pesticide DUKE1992B ; PGE2-Inhibitor X12391547 ; Prostaglandin-Synthesis-Inhibitor IC50=23 uM/ml BBA1428:406 ; Protein-Kinase-C-Inhibitor IC50=25 uM BO2 ; PTK-Inhibitor 10-100 uM IC50=19-37 uM BO2 ; Purgative ED50=>500 mg/kg orl mus IJO16:195 ; Styptic DUKE1992B ; Topoisomerase-II-Inhibitor 1 mM MR371:165 IC50=7 uM/ml BBA1428:406 ; Trichomonicide JE40:111 ; Tyrosine-Kinase-Inhibitor PH2 ; Vasodilator EJP198:211 ; Vasorelaxant EJP198:211
FAT Seed 29,000 - 35,000 ppm DUKE1992A
No activity reported.
PROTEIN Seed 161,000 - 181,000 ppm DUKE1992A
No activity reported.
RHEIN Plant: DUKE1992A
Antibacterial QJC28:155 ; Anticarcinomic IJO16:197 ; Anticariogenic PHZ49:681 ; Anticytomegalovirus ED50=1.1 ug/ml HG40:23 ; Antineoplastic JNM7:51 ; Antiplaque ED50=0.6 ug/ml HG40:23 ; Antiseptic DUKE1992B ; Antitumor LTN-APR-92 ; Antiviral EC50=1.1 PM56(6):651 ED50=0.61 ug/ml HG40:23 ; Calcium-Antagonist 9/10 aloeemodin; Candidicide QJC28:155 ; Cathartic PC29(10):3095 ; Cytotoxic CD50=3.4 ug/ml DUKE1992B ; Fungicide JBH ; Pesticide DUKE1992B ; Proteinase-Inhibitor DUKE1992B ; Purgative ED50=97.5 mg/kg orl mus IJO16:195
RHEIN-GLYCOSIDE Leaf: DUKE1992A
No activity reported.
TANNIN Leaf: DUKE1992A
Anthelmintic JNP59:205 ; Antibacterial JE26:74 ; Anticancer JAF47:397 ; Anticariogenic JNP59:205 ; Antidiarrheic DUKE1992B ; Antidysenteric DUKE1992B ; Antihepatotoxic JNP59:205 ; AntiHIV JNP59:205 ; Antihypertensive JNP59:205 ; Antilipolytic JNP59:205 ; Antimutagenic DUKE1992B ; Antinephritic CPB38:1049 ; Antiophidic EMP5:363 ; Antioxidant 1/3 quercetin JAF47:397 IC50=1.44 ug/ml CPB38:1051 ; Antiradicular 1/3 quercetin JAF47:397 500 mg/kg/day orl mus CPB38:1049 ; Antirenitic CPB38:1049 ; Antitumor; Antitumor-Promoter JAF47:397 ; Antiulcer JNP59:205 ; Antiviral; Cancer-Preventive HG22:14 ; Carcinogenic AHP156 ; Chelator JNP59:205 ; Cyclooxygenase-Inhibitor JNP59:205 ; Glucosyl-Transferase-Inhibitor JNP59:205 ; Hepatoprotective DUKE1992B ; Immunosuppressant RWG29 ; Lipoxygenase-Inhibitor JNP59:205 ; MAO-Inhibitor JNP59:205 ; Ornithine-Decarboxylase-Inhibitor JNP59:205 ; Pesticide DUKE1992B ; Psychotropic CPB38:1049 ; Xanthine-Oxidase-Inhibitor JNP59:205
The source of the experience
Dr Dukes plant databaseConcepts, symbols and science items
Concepts
Symbols
Science Items
Activities and commonsteps
Commonsteps
References
382: Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
411: Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
525: Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
AAC35:2463: Jim Duke's personal files
AEH: De Smet, P.A.G.M., Keller, K., Hansel, R. and Chandler, R.F., eds. 1993. Adverse Effects of Herbal Drugs 2. Springr-Verlag, Berlin. 348pp.
AEH113: Jim Duke's personal files
AEH114: Jim Duke's personal files
AHP156: Jim Duke's personal files
AKT: TIllotson, A. K. (with Abel, Jr., R., Tillotson, N.H., Bajracharya, V.M.B.). 2001. The One Earth Herbal Sourcebook: Everything You Need to Know about Chinese, Western, and Ayurvedic Herbal Treatments. Twin Streams, Kensington Publishing Corp. NY,NY. 596 pp
BBA1428:406: Mueller, S. O., Stopper, H. 1999. Characterization of the Genotoxicity of Anthraquinones in Mammalian Cells. Biochimica & Biophysica Acta, 1428: 406-414.
BO2: Jim Duke's personal files
BOI: Jim Duke's personal files
CAN: Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
CPB38:1049: Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
CPB38:1051: Jim Duke's personal files
DFN:160: Jim Duke's personal files
DUKE1992A: Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.
EJP198:211: Jim Duke's personal files
EMP5:363: Economic & Medicinal Plant Research, 5: 363.
FT63(1):3: Jim Duke's personal files
FT65(4):275: Jim Duke's personal files
FT68(4):291: Jim Duke's personal files
FVT29:765: Jim Duke's personal files
HDN: Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
HG22:14: HerbalGram No. 22 - Spring 1990, page 14.
HG40:23: Jim Duke's personal files
IJE29:230: Jim Duke's personal files
IJO16:195: Jim Duke's personal files
IJO16:197: Jim Duke's personal files
JAF47:397: Jim Duke's personal files
JAFC37:1365: Jim Duke's personal files
JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
JE26:74: Jim Duke's personal files
JE26:82: Jim Duke's personal files
JE27:243: Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
JE28:221: Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
JE40:111: Jim Duke's personal files
JMF5:1: Jim Duke's personal files
JNM7:51: Jim Duke's personal files
JNP33(3):630: Jim Duke's personal files
JNP59:205: Jim Duke's personal files
LAB107: Jim Duke's personal files
LTN-APR-92: Jim Duke's personal files
M11: Merck 11th Edition
M29: Martindale's 29th
M30: Martindale's 30th
MAR: Martindale's 28th
MR371:165: Muller, S. O., Eckert, I., Lutz, W. K., Stopper, H. 1996. Genotoxicity of the Laxative Drug Components Emodin, Aloe-emodin and Danthron in Mammalian Cells: Topoisomerase II Mediated? Mutat Res, 371: 165-173.
PC29(10):3095: Jim Duke's personal files
PC29(5):1667: Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
PEP: Pakistan Encyclopedia Planta Medica. 1986.
PH2: Jim Duke's personal files
PHM9:52: Jim Duke's personal files
PHZ49:681: Jim Duke's personal files
PJB1(1):174: Jim Duke's personal files
PJB1(2):287: Jim Duke's personal files
PM56(6):651: Jim Duke's personal files
PMP23:60: Jim Duke's personal files
PS131:95: Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
PS75:161: Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
QJC28:155: Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
RWG29: Jim Duke's personal files
X10478467: Jim Duke's personal files
X10967452: Jim Duke's personal files
X11988857: Jim Duke's personal files
X12391547: Jim Duke's personal files
X17350814: Jim Duke's personal files
X17358014: Jim Duke's personal files
X17978503: Jim Duke's personal files
X18563353: Jim Duke's personal files
X19291397: Jim Duke's personal files
ppm = parts per million
tr = trace
Sun Nov 8 07:35:16 EST 2015