Observations placeholder
Zavesca
Identifier
020392
Type of Spiritual Experience
Background
Gaucher's disease or Gaucher disease (GD) is a genetic disorder in which glucocerebroside (a sphingolipid, also known as glucosylceramide) accumulates in cells and certain organs. The disorder is characterized by bruising, fatigue, anemia, low blood platelet count and enlargement of the liver and spleen, and is caused by a hereditary deficiency of the enzyme glucocerebrosidase (also known as glucosylceramidase), which acts on glucocerebroside. When the enzyme is defective, glucocerebroside accumulates, particularly in white blood cells and especially in macrophages (mononuclear leukocytes). Glucocerebroside can collect in the spleen, liver, kidneys, lungs, brain, and bone marrow.
A description of the experience
Miglustat (OGT 918, N-butyl-deoxynojirimycin) and is used primarily to treat type I Gaucher disease (GD1). It is marketed under the trade name Zavesca.
Adverse effects
Serious side effects include pain, burning, numbness or tingling in the hands, arms, legs, or feet; shaking hands that cannot be controlled; changes in vision; and easy bruising or bleeding. Common side effects include gastrointestinal effects (including diarrhea, stomach pain or bloating, gas, loss of appetite, weight loss, upset stomach, vomiting, constipation), dry mouth, muscular effects (including weakness, muscle cramps, especially in the legs, feeling of heaviness in the arms or legs, unsteadiness when walking), back pain, dizziness, nervousness, headache, memory problems, and difficult or irregular menstruation (period)
On Feb, 18, 2016: 368 people reported to have side effects when taking Zavesca. Among them, 5 people (1.36%) have Hallucination.
Time on Zavesca when people have Hallucination :
| < 1 month | 1 - 6 months | 6 - 12 months | 1 - 2 years | 2 - 5 years | 5 - 10 years | 10+ years | |
| Hallucination | 0.00% | 100.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Gender of people who have Hallucination when taking Zavesca :
| Female | Male | |
| Hallucination | 0.00% | 100.00% |
Age of people who have Hallucination when taking Zavesca :
| 0-1 | 2-9 | 10-19 | 20-29 | 30-39 | 40-49 | 50-59 | 60+ | |
| Hallucination | 0.00% | 0.00% | 0.00% | 53.85% | 46.15% | 0.00% | 0.00% | 0.00% |
On Feb, 18, 2016: 368 people reported to have side effects when taking Zavesca. Among them, 22 people (5.98%) have Death.
Time on Zavesca when people have Death :
| < 1 month | 1 - 6 months | 6 - 12 months | 1 - 2 years | 2 - 5 years | 5 - 10 years | 10+ years | |
| Death | 0.00% | 0.00% | 40.00% | 0.00% | 0.00% | 60.00% | 0.00% |
Gender of people who have Death when taking Zavesca :
| Female | Male | |
| Death | 61.11% | 38.89% |
Age of people who have Death when taking Zavesca :
| 0-1 | 2-9 | 10-19 | 20-29 | 30-39 | 40-49 | 50-59 | 60+ | |
| Death | 0.00% | 50.00% | 28.57% | 7.14% | 14.29% | 0.00% | 0.00% | 0.00% |
Top conditions involved for these people :
- Niemann-pick disease (12 people, 54.55%)
- Gaucher's disease (5 people, 22.73%)
- Tay-sachs disease (3 people, 13.64%)