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Suxamethonium chloride (INN), also known as suxamethonium or succinylcholine, is a nicotinic acetylcholine receptor agonist, used to induce muscle relaxation and short-term paralysis, usually to facilitate tracheal intubation. Suxamethonium is sold under the trade names Anectine and Quelicin. It is sometimes used in combination with analgesics and sedatives for euthanasia and immobilization of horses. It is colloquially referred to as "sux" in hospital settings

Side effects

Side effects include malignant hyperthermia, muscle pains, acute rhabdomyolysis with high blood levels of potassium transient ocular hypertension, constipation and changes in cardiac rhythm, including slow heart rate, and cardiac arrest. In patients with neuromuscular disease or burns, a single injection of suxamethonium can lead to massive release of potassium from skeletal muscles, potentially resulting in cardiac arrest. Conditions having susceptibility to suxamethonium-induced high blood potassium are burns, closed head injury, acidosis, Guillain–Barré syndrome, cerebral stroke, drowning, severe intra-abdominal sepsis, massive trauma, myopathy, and tetanus.

Suxamethonium does not produce unconsciousness or anesthesia, and its effects may cause considerable psychological distress while simultaneously making it impossible for a patient to communicate. Therefore, administration of the drug to a conscious patient is contraindicated.

On Jan, 28, 2016: 1,154 people reported to have side effects when taking Succinylcholine chloride. Among them, 6 people (0.52%) have Hallucination.

On Jan, 26, 2016: 1,154 people reported to have side effects when taking Succinylcholine chloride. Among them, 81 people (7.02%) have Death.

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