Observations placeholder

Sodium nitroprusside is an inorganic compound with the formula Na2[Fe(CN)5NO], usually encountered as the dihydrate, Na2[Fe(CN)5NO]·2H2O This red-colored sodium salt dissolves in water ethanol to give solutions containing the free complex dianion [Fe(CN)5NO]2−.

This compound is used as a drug. In this role it is abbreviated SNP, and it has tradenames like Nitropress. It acts as a drug by releasing nitric oxide; it belongs to the class of NO-releasing drugs as a result. This drug is used as a vasodilator to reduce blood pressure. Sodium nitroprusside is also used as an analytical reagent for the detection of methyl ketones, and for the detection of amines that are often found in illicit drugs. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.

Adverse effects

Adverse effects by incidence and severity

Common

• Bradyarrhythmia (low heart rate)
• Hypotension (low blood pressure)
• Palpitations
• Tachyarrhythmia (high heart rate)
• Apprehension
• Restlessness
• Confusion
• Dizziness
• Headache
• Somnolence
• Rash
• Sweating
• Thyroid suppression
• Muscle twitch
• Oliguria
• Renal azotemia

Unknown frequency

• Nausea
• Retching
• Anxiety
• Chest discomfort
• Paraesthesial warmth
• Abdominal pain
• Orthostatic hypotension
• ECG changes
• Skin irritation
• Flushing
• Injection site erythema
• Injection site streaking

Serious

• Ileus
• Reduced platelet aggregation
• Haemorrhage
• Increased intracranial pressure
• Metabolic acidosis
• Methaemoglobinaemia
• Cyanide poisoning
• Thiocyanate toxicity

On Feb, 8, 2016: 262 people reported to have side effects when taking Sodium nitroprusside. Among them, 37 people (14.12%) have Death.

Time on Sodium nitroprusside when people have Death  :

Gender of people who have Death when taking Sodium nitroprusside  :