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Observations placeholder

Nexavar

Identifier

019686

Type of Spiritual Experience

Hallucination

Number of hallucinations: 33

Background

A description of the experience

Sorafenibas Nexavar is a kinase inhibitor drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), and radioactive iodine resistant advanced thyroid carcinoma.

Adverse effects by frequency
Note: Potentially serious side effects are in bold.
Very common (>10% frequency)

  • Lymphopenia
  • Hypophosphataemia
  • Haemorrhage
  • Hypertension
  • Diarrhea
  • Rash
  • Alopecia (hair loss; occurs in roughly 30% of patients receiving sorafenib)
  • Hand-foot syndrome
  • Pruritus (itchiness)
  • Erythema
  • Increased amylase
  • Increased lipase
  • Fatigue
  • Pain
  • Nausea
  • Vomiting

Common (1-10% frequency)

  • Leucopoenia
  • Neutropoenia
  • Anaemia,Thrombocytopenia
  • Anorexia (weight loss)
  • Hypocalcaemia
  • Hypokalaemia
  • Depression
  • Peripheral sensory neuropathy
  • Tinnitus
  • Congestive heart failure
  • Myocardial infarction,Myocardial ischaemia
  • Hoarseness
  • Constipation
  • Stomatitis
  • Dyspepsia
  • Dysphagia
  • Dry skin
  • Exfoliative dermatitis
  • Acne
  • Skin desquamation
  • Arthralgia
  • Myalgia
  • Renal failure
  • Proteinuri
  • Erectile dysfunction
  • Asthenia (weakness)
  • Fever
  • Influenza-like illness
  • Transient increase in transaminase

Uncommon (0.1-1% frequency)

  • Folliculitis
  • Infection
  • Hypersensitivity reactions
  • Hypothyroidism
  • Hyperthyroidism
  • Hyponatraemia
  • Dehydration
  • Reversible posterior leukoencephalopathy
  • Hypertensive crisis
  • Rhinorrhoea
  • Interstitial lung disease-like event
  • Gastro-oesophageal reflux disease (GORD)
  • Pancreatiti
  • Gastritis
  • Gastrointestinal perforation
  • Increase in bilirubin leading, potentially, to jaundice
  • Cholecystitis
  • Cholangitis
  • Eczema
  • Erythema multiforme
  • Keratoacanthoma
  • Squamous cell carcinoma
  • Gynaecomastia (swelling of the breast tissue in men)
  • Transient increase in blood alkaline phosphatase
  • INR abnormal
  • Prothrombin level abnormal
  • bulbous skin reaction

Rare (0.01-0.1% frequency)

  • QT interval prolongation
  • Angiooedem
  • Anaphylactic reaction
  • Hepatitis
  • Radiation recall dermatitis
  • Stevens-Johnson syndrom
  • Leucocytoclastic vasculitis
  • Toxic epidermal necrolysis
  • Nephrotic syndrome
  • Rhabdomyolysis

On Dec, 24, 2016    16,152 people reported to have side effects when taking Nexavar.
Among them, 33 people (0.2%) have Hallucination

Time on Nexavar when people have Hallucination  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Hallucination 76.19% 23.81% 0.00% 0.00% 0.00% 0.00% 0.00%

Gender of people who have Hallucination when taking Nexavar  :

  Female Male
Hallucination 14.29% 85.71%

Age of people who have Hallucination when taking Nexavar  :

  0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Hallucination 0.00% 0.00% 0.00% 0.00% 2.50% 2.50% 30.00% 65.00%

 

On Jan, 21, 2016: 12,257 people reported to have side effects when taking Nexavar. Among them, 615 people (5.02%) have Death.

Time on Nexavar when people have Death  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Death 53.33% 36.97% 4.24% 5.45% 0.00% 0.00% 0.00%

Gender of people who have Death when taking Nexavar  :

  Female Male
Death 25.00% 75.00%

Age of people who have Death when taking Nexavar  :

  0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Death 0.00% 0.28% 0.00% 0.28% 1.52% 6.22% 29.46% 62.24%

 

 

The source of the experience

eHealthme

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Activities

Overloads

Alopecia
Chemotherapy drugs

Commonsteps

References