Observations placeholder
Guanfacine Hydrochloride
Identifier
019097
Type of Spiritual Experience
Background
A description of the experience
Guanfacine (brand name Estulic, Tenex and the extended release Intuniv) is a sympatholytic drug used in the treatment of attention deficit hyperactivity disorder (ADHD) and hypertension (not to be confused with guaifenesin, an expectorant). It is a selective α2A receptor agonist. These receptors are concentrated heavily in the prefrontal cortex and the locus coeruleus, with the potential to improve attention resulting from interaction with receptors in the former Guanfacine lowers both systolic and diastolic blood pressure by activating the central nervous system α2A norepinephrine autoreceptors, which results in reduced peripheral sympathetic outflow and thus a reduction in peripheral sympathetic tone
Adverse effects incidence:
Very common (>10% incidence) adverse effects include:
- Xerostomia (dry mouth)
- Somnolence (sleepiness)
- Fatigue
- Dizziness
- Headache
- Constipation
- Abdominal pain
Common (1-10% incidence) adverse effects include:
- Alopecia (hair loss)
- Asthenia (weakness)
- Bradycardia (low heart rate)
- Confusion
- Increased appetite
- Depression
- Dermatitis
- Diaphoresis (sweating without a physiologic reason)
- Dizziness
- Dyspepsia (indigestion)
- Dysphagia (being unable to swallow)
- Dyspnoea (air hunger)
- Hypokinesia
- Hypotension (low blood pressure)
- Impotence
- Insomnia
- Irritability
- Leg cramps
- Lethargy
- Nausea
- Palpitations
- Pruritus (itching)
- Tachycardia (high heart rate)
- Weakness
Unknown frequency adverse effects include:
- Abnormal liver function tests
- Agitation
- Alterations in taste
- Anxiety
- Arthralgia (joint pain)
- Blurred vision
- Chest pain
- Confusion
- Diarrhoea
- Exfoliation
- Exfoliative dermatitis
- Hallucinations
- Impotence
- Leg pains
- Malaise
- Myalgia (muscle pain)
- Nervousness
- Nocturia (waking to urinate)
- Oedema (swelling)
- Orthostatic hypotension
- Paresthesia (pins and needles)
- Rash
- Tremor
- Urinary frequency
- Vertigo (dizziness)
On Nov, 22, 2015: 345 people reported to have side effects when taking Guanfacine hydrochloride. Among them, 7 people (2.03%) have Hallucination.
Time on Guanfacine hydrochloride when people have Hallucination :
| < 1 month | 1 - 6 months | 6 - 12 months | 1 - 2 years | 2 - 5 years | 5 - 10 years | 10+ years | |
| Hallucination | 33.33% | 0.00% | 33.33% | 0.00% | 33.33% | 0.00% | 0.00% |
Gender of people who have Hallucination when taking Guanfacine hydrochloride :
| Female | Male | |
| Hallucination | 25.00% | 75.00% |
Age of people who have Hallucination when taking Guanfacine hydrochloride :
| 0-1 | 2-9 | 10-19 | 20-29 | 30-39 | 40-49 | 50-59 | 60+ | |
| Hallucination | 0.00% | 0.00% | 60.00% | 0.00% | 0.00% | 40.00% | 0.00% | 0.00% |