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Observations placeholder

Dr Duke's list of Chemicals and their Biological Activities in: Quassia amara L. (Simaroubaceae) -- Bitterwood, Quassia, Amargo

Identifier

019145

Type of Spiritual Experience

Background

A description of the experience

Chemicals and their Biological Activities in: Quassia amara L. (Simaroubaceae) -- Bitterwood, Quassia


Chemicals

18-HYDROXYQUASSIN Wood: DUKE1992A

No activity reported.

ALKALOIDS Wood 2,500 ppm; DUKE1992A

No activity reported.

BETA-SITOSTENONE Wood: DUKE1992A

No activity reported.

BETA-SITOSTEROL Wood: DUKE1992A

Androgenic DUKE1992B ; Angiogenic X11988857 ; Anorexic MAR ; Antiadenomic M11 ; Antiandrogenic JE28:221 ; Antibacterial QJC28:155 ; Anticancer (Breast) PS131:95 ; Anticancer (Cervix) PJB1(2):287 ; Anticancer (Lung) PJB1(2):287 ; Antiedemic IC54=320 mg/kg orl DFN:160 ; Antiestrogenic JE28:221 ; Antifeedant 382 ; Antifertility JE28:221 ; Antigonadotrophic JE28:221 ; Antihyperlipoproteinaemic JBH ; Antiinflammatory; Antileukemic PJB1(2):287 ; Antilymphomic PJB1(2):287 ; Antimutagenic 250 ug/ml JAFC37:1365 ; Antiophidic 2.3 mg mus EMP5:363 ; Antioxidant IC44=10 uM JMF5:1 ; Antiprogestational JE28:221 ; Antiprostaglandin 30 mg/day/12 wks FT68(4):291 ; Antiprostatadenomic M11 ; Antiprostatitic 10-20 mg 3 x/day/orl man; Antipyretic HDN ; Antitumor (Breast) PS131:95 ; Antitumor (Cervix) PJB1(2):287 ; Antitumor (Lung) PJB1(2):287 ; Antiviral PS75:161 ; Apoptotic X17350814 ; Artemicide LC50=110 ppm PC29(5):1667 ; Cancer-Preventive 525 ; Candidicide QJC28:155 ; Caspase-8-Inducer X17358014 ; Estrogenic PHM9:52 ; Febrifuge HDN ; Gonadotrophic JE28:221 ; Hepatoprotective PMP23:60 ; Hypocholesterolemic 2-6 g/man/day/orl M30 9-3,330 mg/man/day/orl MAR ; Hypoglycemic JE27:243 ; Hypolipidemic 2-6 g/day; Pesticide DUKE1992B ; Spermicide JE28:221 ; Ubiquiot JBH ; Ulcerogenic 500 mg/kg ipr rat FT63(1):3

CALCIUM-TARTRATE Root: DUKE1992A

No activity reported.

EO Root: DUKE1992A

No activity reported.

GALLIC-ACID Root: DUKE1992A

ACE-Inhibitor IC50=7.7 mM/l; Analgesic FT63(3):195 ; Antiadenovirus EMP5:194 ; Antiallergenic IAA94:262 ; Antianaphylactic JBH ; Antiangiogenic X15884816 ; Antiasthmatic W&B ; Antibacterial MIC=1,000 ug/ml FT65(2):185 ; Antibronchitic IAA94:262 ; Anticancer; Anticarcinomic ED50=3 DUKE1992B ; Antiescherichic PR14:561 ; Antifibrinolytic EMP1:53 ; Antiflu EMP5:194 ; Antihepatotoxic PCF:93 ; Antiherpetic EC50=>10 ug/ml PCF:180 ; AntiHIV PCF:180 ; Antiinflammatory PM58(6):499 ; Antileishmanic EC50=4.4 ug/ml PR15:122 ; AntiMRSA X9145218 ; Antimutagenic EMP6:235 ; Antinitrosaminic AFR27:217 ; Antioxidant 2/3 BHA JAF50:889 7 x quercetin JAF47:397 IC44=33 ppm PCF:218 ; Antiperiodontitic 10 ug/ml X2142592 ; Antiperoxidant IC50=69 uM; Antipolio EMP5:194 ; Antiproteolytic 10 ug/ml X2142592 ; Antiradicular 7 x quercetin JAF47:397 IC50=4.9 uM JAF50:7022 ; Antiseptic 411 ; Antistaphylococcic MIC=1,000 ug/ml FT65(2):185 ; Antitumor; Antitumor-Promoter JAF47:397 ; Antiviral; Apoptotic BO2 ; Astringent 411 ; Bacteristat PR4(5):198 ; Bronchodilator JBH ; Cancer-Preventive 525 ; Candidicide PR14:561 ; Carcinogenic DUKE1992B ; Choleretic JBH ; Cyclooxygenase-Inhibitor RWG141 ; Cytotoxic 500 uM JAF50:850 ; Floral-Inhibitor JBH ; Gram(+)icide MIC=1,000 ug/ml JE42:95 ; Gram(-)icide JE42:95 ; Hemostat JE26:83 ; Hepatoprotective HDN ; Immunomodulator PR15:122 ; Immunostimulant TEA ; Immunosuppressant; Insulin-Sparing JBH ; Myorelaxant JBH ; Nephrotoxic M29 ; NO-Inhibitor IC-26=250 uM JAF50:850 ; Pesticide DUKE1992B ; Styptic DUKE1992B ; Topoisomerase-I-Inhibitor BPB20:1017 ; Xanthine-Oxidase-Inhibitor IC50=24 uM CPB38:1225

ISOQUASSIN Wood: DUKE1992A

No activity reported.

MALIC-ACID Root: DUKE1992A

Antiatherosclerotic X11413687 ; Antibacterial PR14:303 ; Antifibromyalgic 300 mg 3x/day PIL ; Antioxidant Synergist M11 ; Antiseborrheic LRN-JUN89 ; Antiseptic M29 ; Antitubercular PR14:303 ; Antitumor EMP6:235 ; Bacteristat DUKE1992B ; Bruchiphobe 382 ; Hemopoietic DUKE1992B ; Laxative? LRN-SEP91 ; Mycobactericide PR14:303 ; Pesticide DUKE1992B ; Sialogogue M29

NEOQUASSIN Wood: DUKE1992A

No activity reported.

POTASSIUM-ACETATE Wood: DUKE1992A

FLavor FEMA 1-2 ARC

QUASSIN Wood 1,000 - 2,000 ppm DUKE1992A

Amebicide 100 ppm DUKE1992B ; Apertif DUKE1992B ; Emetic OMM ; Insecticide GMJ ; Pesticide DUKE1992B

QUASSINOL Wood: DUKE1992A

No activity reported.

QUASSOL Wood: DUKE1992A

No activity reported.

The source of the experience

Dr Dukes plant database

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Commonsteps

References

382: Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.

411: Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.

525: Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.

AFR27:217: Jim Duke's personal files

ARC: Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Note: Most ARC numerical data were in mg/dl. I know of no other plant where zinc is more prevalent than other minerals and protein. These data should be viewed as suspect.

BO2: Jim Duke's personal files

BPB20:1017: Hamada, S. I., Kataoka, T., Woo, J. T., Yamada, A., Yoshida, T., Nishimura, T., Otake, N., Nagai, K. 1997. Immunosuppressive Effects by Gallic Acid and Chebulagic Acid on CTL-Mediated Cytotoxicity. Biol Pharm Bull, 20: 1017-1019.

CPB38:1225: Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229

DFN:160: Jim Duke's personal files

DUKE1992A: Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.

EMP1:53: Economic & Medicinal Plant Research, 1: 53.

EMP5:194: Economic & Medicinal Plant Research, 5: 194.

EMP5:363: Economic & Medicinal Plant Research, 5: 363.

EMP6:235: Economic & Medicinal Plant Research, 6: 235.

FT63(1):3: Jim Duke's personal files

FT63(3):195: Jim Duke's personal files

FT65(2):185: Jim Duke's personal files

FT68(4):291: Jim Duke's personal files

GMJ: Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.

HDN: Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.

IAA94:262: Dorsch, W., Wagner, H. New Antiasthmatic Drugs from Traditional Medicine? Int Arch Allergy Appl Immunol 94: 262-265, 1991.

JAF47:397: Jim Duke's personal files

JAF50:7022: Jim Duke's personal files

JAF50:850: Jim Duke's personal files

JAF50:889: Jim Duke's personal files

JAFC37:1365: Jim Duke's personal files

JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

JE26:83: Jim Duke's personal files

JE27:243: Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.

JE28:221: Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.

JE42:95: Jim Duke's personal files

JMF5:1: Jim Duke's personal files

LRN-JUN89: Jim Duke's personal files

LRN-SEP91: Lawrence Review of Natural Products, Sep-91.

M11: Merck 11th Edition

M29: Martindale's 29th

M30: Martindale's 30th

MAR: Martindale's 28th

OMM: Oriental Materia Medica (three volumes by Dr. Hsu and collaborators)

PC29(5):1667: Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.

PCF:180: Jim Duke's personal files

PCF:218: Jim Duke's personal files

PCF:93: Okuda, T., Yoshida, T., and Hatano, T. Antioxidant Effects of Tannins and Related Polyphenols. Phenolic Compounds in Food and Their Effects on Health, Ch.7 p.93.

PHM9:52: Jim Duke's personal files

PIL: Jim Duke's personal files

PJB1(2):287: Jim Duke's personal files

PM58(6):499: Kroes, B.H., et al. 1991. Anti-Inflammatory Activity of Gallic Acid. Planta Medica, 58(6): 499.

PMP23:60: Jim Duke's personal files

PR14:303: Jim Duke's personal files

PR14:561: Jim Duke's personal files

PR15:122: Jim Duke's personal files

PR4(5):198: Lamikanra, A., Ogundaini, A.O., and Ogungbamila*, F.O. Antibacterial Constituents of Alchornea cordifolia Leaves. Phytotherapy Research 4(5): 198.

PS131:95: Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.

PS75:161: Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.

QJC28:155: Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.

RWG141: Jim Duke's personal files

TEA: McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.

W&B: Watt, J.M., and Breyer-Brandwijk, M.G. The Medicinal and Poisonous Plants of Southern and Eastern Africa. 1962.

X11413687: Jim Duke's personal files

X11988857: Jim Duke's personal files

X15884816: Jim Duke's personal files

X17350814: Jim Duke's personal files

X17358014: Jim Duke's personal files

X2142592: Jim Duke's personal files

X9145218: Jim Duke's personal files

ppm = parts per million
tr = trace