WHAT AND WHERE IS HEAVEN?

Does heaven exist? With well over 100,000 plus recorded and described spiritual experiences collected over 15 years, to base the answer on, science can now categorically say yes. Furthermore, you can see the evidence for free on the website allaboutheaven.org.

Available on Amazon
https://www.amazon.com/dp/B086J9VKZD
also on all local Amazon sites, just change .com for the local version (.co.uk, .jp, .nl, .de, .fr etc.)

VISIONS AND HALLUCINATIONS

This book, which covers Visions and hallucinations, explains what causes them and summarises how many hallucinations have been caused by each event or activity. It also provides specific help with questions people have asked us, such as ‘Is my medication giving me hallucinations?’.

Available on Amazon
https://www.amazon.com/dp/B088GP64MW 
also on all local Amazon sites, just change .com for the local version (.co.uk, .jp, .nl, .de, .fr etc.)

Observations placeholder

Methotrexate and Trexall

Identifier

017729

Type of Spiritual Experience

Hallucination

Number of hallucinations: 265

Background

Reversible dementia temporally associated with intraventricular therapy with methotrexate in a child with acute myelogenous leukaemia - Pizzo PA  Bleyer WA, Poplack DG, Leventhal BG.

During maintenance therapy with intraventricular methotrexate, progressive dementia developed in a child with meningeal leukemia.  Cerebrospinal fluid levels of MTX were in the nontoxic range and neurologic evaluation failed to demonstrate anatomic obstruction, infection, or folate depletion. The patient's symptoms gradually resolved when the methotrexate was discontinued, suggesting that methotrexate neurotoxicity may occur in the absence of an elevated CSF concentration of MTX.

Severe neurological damage associated with methotrexate therapy - Kay HE, Knapton PJ, O'Sullivan JP, Wells DG, Harris RF, Innes EM, Stuart J, Schwartz FC, Thompson EN.  Lancet. 1971 Sep 4;2(7723):542.  PMID: 4105681

A description of the experience

Methotrexate (oral) (meth oh TREX ate) Brand Names: Rheumatrex Dose Pack, Trexall is an immunosuppressant.  Methotrexate interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.

Methotrexate is abbreviated MTX and formerly known as amethopterin, Methotrexate is an antimetabolite and antifolate drug. It is used in the treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions.   It acts by inhibiting the metabolism of folic acid.

The most common adverse effects include: ulcerative stomatitis, low white blood cell count and thus predisposition to infection, nausea, abdominal pain, fatigue, fever, dizziness and rarely pulmonary fibrosis.  Central nervous system reactions to methotrexate have been reported – and is serious. Penicillins may decrease the elimination of methotrexate and thus increase the risk of toxicity.

  • Chemotherapy 
  • Autoimmune disease treatment  - Methotrexate is also used as a treatment for some autoimmune diseases including: rheumatoid arthritis, psoriasis, psoriatic arthritis, and Crohn's disease. Although methotrexate was originally designed as a chemotherapy drug (in high doses), it is used in low-doses in the treatment of autoimmune diseases. It is frequently used in the treatment of rheumatoid arthritis.  For the treatment of rheumatoid arthritis, inhibition of DHFR is not thought to be the main mechanism, but rather the inhibition of enzymes involved in purine metabolism, leading to accumulation of adenosine, or the inhibition of T cell activation
  • Pregnancy termination - Finally, Methotrexate is commonly used (generally in combination with misoprostol) to terminate pregnancies during the early stages

On Aug, 13, 2015: 65 people reported to have side effects when taking Methotrexate preservative free. Among them, 1 people (1.54%) has Hallucination

On Jan, 22, 2017 140 people reported to have side effects when taking Methotrexate Lpf.  Among them, 1 person (0.71%) has Hallucination

On Jan, 02, 2017 11,813 people reported to have side effects when taking Methotrexate Sodium.  Among them, 7 people (0.06%) have Hallucination

On Jan, 03, 2017 11,813 people reported to have side effects when taking Methotrexate Sodium.  Among them, 8 people (0.07%) have Hallucination, Auditory

On Jan, 04, 2017 209,150 people reported to have side effects when taking Methotrexate.  Among them, 248 people (0.12%) have Hallucinations

 

Time on Methotrexate when people have Hallucination :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Hallucination 47.83% 4.35% 8.70% 4.35% 21.74% 0.00% 13.04%

Gender of people who have Hallucination when taking Methotrexate  :

  Female Male
Hallucination 62.04% 37.96%

Age of people who have Hallucination when taking Methotrexate  :

  0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Hallucination 0.00% 6.70% 8.94% 3.91% 8.94% 8.38% 24.58% 38.55%

Severity of Hallucination when taking Methotrexate  :

  least moderate severe most severe
Hallucination 25.00% 25.00% 25.00% 25.00%

How people recovered from Hallucination  :

  while on the drug after off the drug not yet
Hallucination 0.00% 0.00% 100.00%

The source of the experience

eHealthme

Concepts, symbols and science items

Concepts

Symbols

Science Items

Antifolates

Activities and commonsteps

Commonsteps

Hearing voices

References