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Observations placeholder

Antibacterial activity of components from Lomatium californicum

Identifier

017481

Type of Spiritual Experience

Background

A description of the experience

Phytother Res. 2006 Feb;20(2):153-6.

Antibacterial activity of components from Lomatium californicum.

Chou SC1, Everngam MC, Sturtz G, Beck JJ.

Abstract

The isolation, characterization and bioactivity testing of compounds from Lomatium californicum (Nutt.) are described.

Ethyl acetate and hexane extracts of the roots of L. californicum were subjected to vacuum liquid chromatography (VLC), flash column chromatography (FCC) and separation by normal- and reverse-phase high-performance liquid chromatography (HPLC).

Six compounds were isolated successfully and characterized by 1D and 2D nuclear magnetic resonance (NMR) experimentation.

The bioactivity of the known compounds (+)-falcarindiol, coniferyl ferulate, ferulic acid and (Z)-ligustilide were confirmed against the Gram-positive bacteria Bacillus subtilis and Staphylococcus aureus. The known compounds senkyunolide I and trans-neocnidilide were also isolated but in too small a quantity for similar testing.

Copyright 2006 John Wiley & Sons, Ltd.

PMID:  16444670

The source of the experience

PubMed

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Activities

Overloads

Bacterial infection

Suppressions

Biscuit root

Commonsteps

References