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Observations placeholder

Clonidine

Identifier

005096

Type of Spiritual Experience

Hallucination

Number of hallucinations: 321

Background

A description of the experience

Clonidine (trade names Catapres, Kapvay, Nexiclon, Clophelin, and others) is a sympatholytic medication used to treat high blood pressure, attention deficit hyperactivity disorder, anxiety disorders, withdrawal (from either alcohol, opioids, or smoking), migraine, menopausal flushing, diarrhea, and certain pain conditions [sic].

It is classified as a centrally acting α2 adrenergic agonist and imidazoline receptor agonist.

Clonidine  stimulates α2-receptors in the brain, which decreases peripheral vascular resistance, lowering blood pressure. It has specificity towards the presynaptic α2-receptors in the vasomotor center in the brainstem. This binding decreases presynaptic calcium levels, thus inhibiting the release of norepinephrine (NE). The net effect is a decrease in sympathetic tone. It has also been proposed that the antihypertensive effect of clonidine is due to agonism on the I1-receptor (imidazoline receptor), which mediates the sympatho-inhibitory actions of imidazolines to lower blood pressure. Its mechanism of action in the treatment of ADHD is to increase noradrenergic tone in the prefrontal cortex (PFC) directly by binding to postsynaptic α2A adrenergic receptors and indirectly by increasing norepinephrine input from the locus coeruleus.

On Jan, 22, 2017 29,863 people reported to have side effects when taking Clonidine.
Among them, 216 people (0.72%) have Hallucination

On Jan, 29, 2017 29,863 people reported to have side effects when taking Clonidine.
Among them, 4 people (0.01%) have Hallucination, Tactile

On Dec, 31, 2016 29,863 people reported to have side effects when taking Clonidine.
Among them, 101 people (0.34%) have Hallucination, Auditory

Time on Clonidine when people have Hallucinations  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Hallucinations 100.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%

Age of people who have Hallucinations when taking Clonidine  :

  0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Hallucinations 0.00% 5.88% 4.41% 8.82% 4.41% 7.35% 13.24% 55.88%

 

 

On Aug, 4, 2015: 9,255 people reported to have side effects when taking Clonidine. Among them, 357 people (3.86%) have Death.

Time on Clonidine when people have Death  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Death 21.43% 7.14% 7.14% 57.14% 0.00% 0.00% 7.14%

Age of people who have Death when taking Clonidine  :

  0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Death 0.00% 4.88% 8.23% 0.61% 4.57% 9.15% 19.82% 52.74%

 

 

 

The source of the experience

eHealthme

Concepts, symbols and science items

Symbols

Science Items

Activities and commonsteps

Commonsteps

Hearing voices

References