Observations placeholder
Haloperidol and Haldol
Identifier
001495
Type of Spiritual Experience
Number of hallucinations: 259
Background
A description of the experience
Haloperidol ; Haloperidol Decanoate, ; and Haloperidol Lactate also Haldol - Haloperidol is an antipsychotic with very strong antidopaminergic action. It has a high frequency of side effects - dystonias, akathisia, pseudoparkinsonism. It has minor antihistaminic and anticholinergic properties. Haloperidol also has sedative properties. Dopamine receptor antagonism, is mainly of the D2 receptor subtype, and can cause akathisia, psychomotor agitation, anxiety, and restlessness, which ‘may worsen the condition of some patients’.
Haloperidol acts on these receptors: (Ki)
- Dopamine D1 (Silent antagonist)
- Dopamine D5 (Silent antagonist) – Unknown efficiency
- Dopamine D2 (inverse agonist) – 1.55nM
- Dopamine D3 (Inverse agonist) – 0.74nM
- Dopamine D4 (inverse agonist) – 5–9nM
- Sigma 1(Irreversible inactivation by HPP+) – 3nM
- Sigma 2 agonist: 54nM
- 5HT1A receptor agonist – 1927nM
- 5HT2A (Silent antagonist) – 53nM
- 5HT2C (Silent antagonist) – 10,000nM
- 5HT6 (Silent antagonist) – 3666nM
- 5HT7 (Irreversible silent antagonist) – 377.2nM
- Histamine H1 (Silent antagonist) – 1800nM
- Muscarinic M1 (Silent antagonist) – 10,000nM
- Alpha Adrenergic 1a (Silent antagonist) – 12nM
- Alpha Adrenergic 2a (Silent antagonist) – 1130nM
- Alpha Adrenergic 2b (Silent antagonist) – 480nM
- Alpha Adrenergic 2c (Silent antagonist) – 550nM
- NR1\NR2B Subunit containing NMDA receptor antagonist (Ifenprodil site): IC50 – 2,000 nM
On Jul, 29, 2015: 9,421 people reported to have side effects when taking Haldol. Among them, 230 people (2.44%) have Hallucination.
Time on Haldol when people have Hallucination :
| < 1 month | 1 - 6 months | 6 - 12 months | 1 - 2 years | 2 - 5 years | 5 - 10 years | 10+ years | |
| Hallucination | 83.33% | 4.17% | 4.17% | 4.17% | 0.00% | 4.17% | 0.00% |
Gender of people who have Hallucination when taking Haldol :
| Female | Male | |
| Hallucination | 65.00% | 35.00% |
Age of people who have Hallucination when taking Haldol :
| 0-1 | 2-9 | 10-19 | 20-29 | 30-39 | 40-49 | 50-59 | 60+ | |
| Hallucination | 0.00% | 0.47% | 2.79% | 10.70% | 8.84% | 12.09% | 41.40% | 23.72% |
Severity of Hallucination when taking Haldol :
| least | moderate | severe | most severe | |
| Hallucination | 0.00% | 0.00% | 100.00% | 0.00% |
On Aug, 1, 2015: 177 people reported to have side effects when taking Haloperidol. Among them, 8 people (4.52%) have Hallucination.
Time on Haloperidol when people have Hallucination :
| < 1 month | 1 - 6 months | 6 - 12 months | 1 - 2 years | 2 - 5 years | 5 - 10 years | 10+ years | |
| Hallucination | 100.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
On Aug, 10, 2015: 816 people reported to have side effects when taking Haloperidol decanoate. Among them, 11 people (1.35%) have Hallucination.
On Aug, 10, 2015: 213 people reported to have side effects when taking Haloperidol lactate. Among them, 10 people (4.69%) have Hallucination.
Time on Haloperidol lactate when people have Hallucination :
| n/a |
Gender of people who have Hallucination when taking Haloperidol lactate :
| Female | Male | |
| Hallucination | 80.00% | 20.00% |
Age of people who have Hallucination when taking Haloperidol lactate :
| 0-1 | 2-9 | 10-19 | 20-29 | 30-39 | 40-49 | 50-59 | 60+ | |
| Hallucination | 0.00% | 0.00% | 11.11% | 0.00% | 0.00% | 0.00% | 22.22% | 66.67% |