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Observations placeholder

Thioguanine

Identifier

020204

Type of Spiritual Experience

Hallucination

Number of hallucinations: 6

Background

A description of the experience

Tioguanine, also known as thioguanine or 6-thioguanine (6-TG) is a medication used to treat a number of types of leukemia.   It has been used less frequently in recent years because of safety concerns. However, it is becoming more widely used for treating ulcerative colitis and some autoimmune diseases.

Side effects

  • Leukopenia and neutropenia
  • Thrombocytopenia
  • Anemia
  • Anorexia
  • Nausea and vomiting
  • Hepatotoxicity: this manifests as:

Hepatic veno-occlusive disease and nodular regenerative hyperplasia

The major concern that has inhibited the use of thioguanine has been VOD and its histological precursor NRH. The incidence of NRH with thioguanine was reported as between 33-76%.   The risk of ensuing VOD is serious and frequently irreversible so this side effect has been a major concern.

On Feb, 11, 2016: 725 people reported to have side effects when taking Thioguanine. Among them, 6 people (0.83%) have Hallucination.

Time on Thioguanine when people have Hallucination  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Hallucination 100.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%

 

 On Feb, 11, 2016: 725 people reported to have side effects when taking Thioguanine. Among them, 17 people (2.34%) have Death.

The source of the experience

eHealthme

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Activities

Overloads

Chemotherapy drugs
Intestine disease

Commonsteps

References