Observations placeholder
Savella
Identifier
020022
Type of Spiritual Experience
Background
A description of the experience
Milnacipran /milnæsipræn/ (Ixel, Savella, Dalcipran, Toledomin) is a serotonin–norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. It is not approved for the clinical treatment of major depressive disorder in the USA, but it is in other countries.
Side effects
The most frequently occurring adverse reactions (≥ 5% and greater than placebo) were nausea, headache, constipation, dizziness, insomnia, hot flush, hyperhidrosis, vomiting, palpitations, heart rate increase, dry mouth, and hypertension [FDA Savella prescribing information]. Milnacipran can have a significant impact on sexual functions, including both a decrease in sexual desire and ability.
Milnacipran can cause pain of the testicles in men. The incidence of cardiovascular and anticholinergic side effects was significantly lower compared to TCAs as a controlled study with over 3,300 patients revealed. Elevation of liver enzymes without signs of symptomatic liver disease has been infrequent. Mood swing to mania has also been seen and dictates termination of treatment. In psychotic patients emergence of delirium has been noticed. Milnacipran has a low incidence of sedation but improves sleep (both duration and quality) in depressed patients. In agitated patients or those with suicidal thoughts additive sedative/anxiolytic treatment is usually indicated
On Dec, 26, 2016 4,016 people reported to have side effects when taking Savella.
Among them, 43 people (1.07%) have Hallucination
Time on Savella when people have Hallucination :
| < 1 month | 1 - 6 months | 6 - 12 months | 1 - 2 years | 2 - 5 years | 5 - 10 years | 10+ years | |
| Hallucination | 77.27% | 9.09% | 0.00% | 9.09% | 0.00% | 4.55% | 0.00% |
Gender of people who have Hallucination when taking Savella :
| Female | Male | |
| Hallucination | 88.89% | 11.11% |
Age of people who have Hallucination when taking Savella :
| 0-1 | 2-9 | 10-19 | 20-29 | 30-39 | 40-49 | 50-59 | 60+ | |
| Hallucination | 0.00% | 0.00% | 0.00% | 5.26% | 5.26% | 34.21% | 23.68% | 31.58% |
Severity of Hallucination when taking Savella :
| least | moderate | severe | most severe | |
| Hallucination | 0.00% | 0.00% | 100.00% | 0.00% |
How people recovered from Hallucination :
| while on the drug | after off the drug | not yet | |
| Hallucination | 0.00% | 0.00% | 100.00% |
Top conditions involved for these people :
- Fibromyalgia (32 people, 96.97%)
- Attention deficit/hyperactivity disorder (4 people, 12.12%)
On Feb, 7, 2016: 2,817 people reported to have side effects when taking Savella. Among them, 8 people (0.28%) have Death.
Time on Savella when people have Death :
| < 1 month | 1 - 6 months | 6 - 12 months | 1 - 2 years | 2 - 5 years | 5 - 10 years | 10+ years | |
| Death | 60.00% | 20.00% | 20.00% | 0.00% | 0.00% | 0.00% | 0.00% |