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A case of small cerebral cyst and pericentric inversion of chromosome 9 that developed schizophrenia-like psychosis
Identifier
017815
Type of Spiritual Experience
Background
A description of the experience
Psychiatry Clin Neurosci. 1999 Oct;53(5):599-602.
A case of small cerebral cyst and pericentric inversion of chromosome 9 that developed schizophrenia-like psychosis.
Miyaoka T1, Seno H, Itoga M, Ishino H.
Author information
- 1Department of Psychiatry, Shimane Medical University, Izumo, Japan.
Abstract
A case of schizophrenia-like psychosis (psychotic disorder not otherwise specified according to the DSM-IV criteria) with pericentric inversion on chromosome 9 [inv.(9) (p11; q13)] is reported. In this case, a minor brain anomaly, a small cyst in the left subcortex, was observed on magnetic resonance imaging of the brain. In the clinical course, prominent chronic hallucinations were observed; however, there was no evidence of the disorganization of personality, delusion, and deterioration in level of functioning that are usually seen in schizophrenia. This case and a review of the literature indicate that the pericentric region of chromosome 9 might be a potential areas of interest for the aetiology of psychiatric disorders. The phenotype-karyotype relationship of pericentric inversion on chromosome 9 and its relationship to psychosis are discussed.
PMID: 10595686