Pol Merkur Lekarski. 2005 Nov;19(113):651-3.

[The influence of anthocyanins from Aronia melanocarpa on selected parameters of oxidative stress and microelements contents in men with hypercholesterolemia].

[Article in Polish]

Kowalczyk E1, Fijałkowski P, Kura M, Krzesiński P, Błaszczyk J, Kowalski J, Smigielski J, Rutkowski M, Kopff M.

• 1Zakład Fizjologii Człowieka i Biofizyki Uniwersytetu Medycznego w Lodzi. farmak@achilles.wam.lodz.pl

Abstract

THE AIM OF THE STUDY:

Our investigations was to estimate the influence of Aronia anthocyanins (Aronox by Agropharm) on selected parameters of oxidative and antioxidative balance as well as on the concentration of selected metals in red blood cells in men with hipercholesterolaemia.

MATERIAL AND METHODS:

16 men aged 27 +/- 6.4 years old with blood cholesterol concentration on the level of 205-250 mg/dl took 240 mg of anthocyanins a day for 30 days. Before and after the period of anthocyanins administration a blood sample was taken and following parameters were estimated: lead, aluminium, copper and zinc concentration in erythrocytes with the method of atomic emission spectrometry with induced coupling plasma (AES-ICP), concentration of substances reacting with thiobarbituric acid (TBARS) and superoxide dismutase, glutathione peroxidase and catalase activities in hemolysate.

CONCLUSION:

30 days long administration of 240 mg of anthocyanins a day, caused a substantial increase of glutathione peroxidase and catalase activities. The lead, aluminium and copper concentration was decreased while zinc concentration in red blood cells was increased.

PMID:  16498804