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Observations placeholder

Bupropion

Identifier

017329

Type of Spiritual Experience

Hallucination

Number of hallucinations: 45

Background

A description of the experience

Bupropion is also known as Wellbutrin, for which another entry exists, but as the eHealthme site appear to keep separate figures for each name of a drug, then this entry has been created.

It is marketed as both an antidepressant and smoking cessation aid.  It is “ widely used, in a formulation marketed as Zyban, to aid people who are trying to quit smoking”.

Bupropion is “known to affect several different biological targets, and its mechanism of action is only partly understood [sic]”.

There is evidence that bupropion induces the release of norepinephrine and dopamine in addition to inhibiting their reuptake, similarly to other cathinones like amfepramone (diethylpropion).

In addition to its monoaminergic actions, bupropion and its metabolites act as non-competitive antagonists of several neuronal nicotinic acetylcholine receptors (nACh receptors), a property which appears to be importantly involved in both the antidepressant effects of bupropion and its efficacy in smoking cessation.[14][19] Chemically, bupropion belongs to the class of aminoketones and is similar in structure to stimulants such as cathinone and amfepramone, and to phenethylamines in general.”

It is a substituted cathinone (β-ketoamphetamine), and by extension, a substituted amphetamine.

On Jan, 18, 2017 5,995 people reported to have side effects when taking Bupropion Hydrochloride.  Among them, 45 people (0.75%) have Hallucination

Time on Bupropion hydrochloride when people have Hallucinations  :

  < 1 month 1 - 6 months 6 - 12 months 1 - 2 years 2 - 5 years 5 - 10 years 10+ years
Hallucinations 70.00% 20.00% 0.00% 0.00% 10.00% 0.00% 0.00%

Age of people who have Hallucinations when taking Bupropion hydrochloride  :

  0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Hallucinations 0.00% 3.70% 3.70% 14.81% 11.11% 29.63% 22.22% 14.81%

Severity of Hallucinations when taking Bupropion hydrochloride  :

  least moderate severe most severe
Hallucinations 0.00% 33.33% 66.67% 0.00%

The source of the experience

eHealthme

Concepts, symbols and science items

Concepts

Symbols

Science Items

Activities and commonsteps

Commonsteps

References