Observations placeholder

Chemicals and their Biological Activities in: Artemisia absinthium L. (Asteraceae) -- Wormwood

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Chemicals

2,3-DIEPI-ARTABSINOLIDE-C Plant:

No activity reported.

3,6-DIHYDROCHAMAZULENE Essential Oil:

No activity reported.

3,7-DIOXABICYCL-(3,3,0)-OCTANE Plant:

No activity reported.

5,6-DIHYDROCHAMAZULENE Essential Oil:

No activity reported.

5-HYDROXY-3,6,7,3',4'-PENTAMETHOXYFLAVONE Plant:

No activity reported.

ABSINTHIN Leaf:

Insecticide; Larvicide; Toxic

ACHILLICIN Flower:

No activity reported.

ALPHA-THUJONE Leaf 1,750 ppm;

Abortifacient; Antibacterial; Emmenagogue; Insecticide; Larvicide; Pesticide

ANABSIN Plant:

No activity reported.

ANABSININ Plant:

No activity reported.

ANABSINTHIN Plant:

No activity reported.

ARABSIN Plant:

No activity reported.

ARTABASIN Leaf:

No activity reported.

ARTABIN Plant:

No activity reported.

ARTABSINOLIDE Plant:

No activity reported.

ARTEMETIN Leaf 60 ppm;

Antiedemic ED50=67; Antiinflammatory 30-150 mg/kg; Antimalarial (Synergic w artemisinin) IC50=26 uM; Parasiticide IC50=26 uM; Pesticide; Plasmodicide; Protisticide

ARTEMOLINS Plant:

No activity reported.

ARTENISETIN Plant:

No activity reported.

ARTHAMARIDIN Plant:

No activity reported.

ARTHAMARIDININE Plant:

No activity reported.

ARTHAMARIN Plant:

No activity reported.

ARTHAMARININ Plant:

No activity reported.

ASCORBIC-ACID Leaf 1,200 - 2,600 ppm

Acidulant FEMA 6,000; Aldose-Reductase-Inhibitor; Analgesic 5-10 g/day; Angiotensin-Receptor-Blocker; AntiAGE 2,000 mg/day; Antiaggregant; Antiaging 400 mg/day; Antiallergic; Antialzheimeran 2,000-6,000 mg/day; Antiarthritic 0.2-1 g/day; Antiasthmatic 1,000 mg/day; Antiatherosclerotic; Antibacterial; Anticataract 1 g 3x/day 350 mg/day 400 mg/day; Anticervicaldysplasic 1,000-2,000 mg/day; AntiCFS 500-1,000 mg; Anticlimacteric 500-5,000 mg/day; Anticold 1-2 g/man/day; AntiCrohn's 50-100 mg/day/orl/man; AntiCTS 1,000 mg 3x/day; Antidecubitic 500 mg/man/2x/day; Antidementia; Antidepressant 2,000 mg/day; Antidiabetic; Antidote (Aluminum); Antidote (Cadmium); Antidote (Lead); Antidote (Paraquat); Antieczemic 3.5-5 g/day; Antiedemic 1 g/man/day; Antiencephalitic; Antiendometriotic 2,000 mg/day; Antifatigue 500-1,000 mg; Antifibrotic 1,000-2,000 mg; Antigallstone 1,000-3,000 mg/day; Antigastritic; Antigingivitic; Antiglaucomic 2 g/day; Antihangover 1,000 mg; Antihemorrhagic 1 g/man/day; Antihepatitic 2-6 g/man/day; Antihepatotoxic; Antiherpetic 1-5 g/day; Antihistaminic 2 g/day orl man; Antihypertensive; Antiinfertility 1 g/day; Antiinflammatory; Antilepric 1.5 g/man/day; Antilithic 1,000-3,000 mg/day; AntiLyme 500-2,000 mg; Antimaculitic; Antimeasles; Antimenopausal 500-5,000 mg/day; Antimigraine; Antimutagenic; Antineuramidase; Antinitrosic 1 g/man/day; Antiobesity 1 g 3x/day; Antiorchitic; Antiosteoarthritic 1 g 2x/day; Antiosteoporotic 500 mg/day; Antioxidant 100 ppm; Antiparkinsonian 1 g 2-3x/day; Antiparotitic; Antiperiodontitic 1 g 2x/day; Antipneumonic; Antipodriac; Antipoliomyelitic; Antipyretic; Antiradicular; AntiRaynaud's 500 mg 1-2x/day; Antiretinotic; Antirheumatic; Antirhinitic 1,000 mg 3x/day; Antiscorbutic 10 mg/man/day; Antiseptic 4-8 g/day MIC=3.3-217 mg/ml; Antishingles; Antispasmodic 500-5,000 mg/day; Antistress 500-1,000 mg; Antisyndrome-X 1-4 g/day; Antitumor (Gastric); Antitumor (Lung); Antiulcer; Antiviral 1-5 g/day; Apoptotic 1-10 mM; Asthma-preventive 1,000 mg/day/orl; Beta-Adrenergic Receptor Blocker; Beta-Glucuronidase-Inhibitor 1.5 g/day/man; Calcium-Antagonist; Cancer-Preventive; Cardioprotective; Cold-preventive 1-2 g/day; Collagenic; Detoxicant; Diuretic 700 mg/man/orl; Fistula-Preventive; Hypocholesterolemic 300-1,000 mg/day; Hypoglycemic; Hypotensive 1,000 mg/man/day; Immunomodulator; Immunostimulant; Interferonogenic; Lithogenic; Mucolytic 1 g/woman/day; Pesticide; Uricosuric 4 g/man/day; Urinary-Acidulant; Vasodilator; Vulnerary

ASH Seed 66,000 ppm;

No activity reported.

BETA-CAROTENE Leaf 500 ppm;

Allergenic; Androgenic?; Antiacne; Antiaging; Antiarthritic; Antiasthmatic; Anticancer; Anticarcinomic; Anticervicaldysplasic; Anticoronary 50 mg/man/2 days; Antihyperkeratotic; Antiichythyotic; Antileukoplakic; Antilipoperoxidant IC71=50 ug/ml; Antilupus 150 mg/man/day/2 mos; Antimaculitic; Antimastitic; Antimutagenic; Antioxidant; Antiozenic; Antipapillomic; Antiphotophobic 30-300 mg/man/day; Antipityriasic; AntiPMS; Antiporphyric; Antiproliferant; Antipsoriac; Antiradicular; Antirheumatic; Antistress; Antitumor; Antitumor (Breast) IC45=60 ug/ml; Antitumor (CNS) IC43=45 ug/ml; Antitumor (Colon); Antitumor (Lung) IC30=60 ug/ml; Antitumor (Prostate); Antitumor (Stomach) IC26=45 ug/ml; Antiulcer 12 mg 3x/day/man/orl 15,000-25,000 IU/day; Antixerophthalmic; Cancer-Preventive 22 ppm; Chemopreventive; Colorant; COX-1-Inhibitor IC78=50 ug/ml; COX-2-Inhibitor IC82=50 ug/ml; Gastroprotective; Immunostimulant 180 mg/man/day/orl; Interferon-Synergist; Mucogenic; Phagocytotic; Prooxidant 20 ug/g; Thymoprotective; Ubiquiot

BETA-CARYOPHYLLENE Plant:

No activity reported.

BETA-THUJONE Leaf 1,750 ppm;

Abortifacient; Antibacterial; Emmenagogue; Insectifuge; Pesticide

BISABOLENE Plant:

No activity reported.

CADINENE Plant:

Antifeedant; FLavor FEMA 400-4,000; Perfumery; Pesticide

CAMPHENE Plant:

Allelopathic; Antilithic?; Antioxidant; Expectorant; FLavor FEMA 15-175; Hypocholesterolemic?; Insectifuge; Pesticide; Spasmogenic

CHAMAZULENE Leaf 1,700 ppm;

Analgesic; Antiallergic; Antiinflammatory; Antileukotriene; Antioxidant; Antipyretic; Antiseptic; Antispasmodic; Pesticide; Vulnerary

CHLOROGENIC-ACID Plant:

Aldose-Reductase-Inhibitor IC50=1.8 uM rat (strong activity); Allelochemic; Allergenic; Analgesic; Antiatherosclerotic; Antibacterial; Anticancer (Colon); Anticancer (Forestomach); Anticancer (Liver); Anticancer (Skin); Anticarcinogenic; Antidiabetic; AntiEBV; Antifeedant; Antigenotoxic; Antigonadotropic; Antihemolytic 10 uM; Antihepatotoxic; Antiherpetic; Antihistaminic; AntiHIV; Antihypercholesterolemic; Antihyperthyroid; Antiinflammatory; AntiLegionella; Antileukotriene; Antimelanogenic; Antimutagenic; Antinitrosaminic; Antioxidant IC50=54.2 uM IC53=200 ppm IC80=12 uM; Antiperoxidant IC50=36 uM; Antipolio; Antiradicular 10 uM 9 x quercetin; Antiseptic; Antisunburn; Antithyroid; Antitumor; Antitumor (Colon); Antitumor (Forestomach); Antitumor (Liver); Antitumor (Skin); Antitumor-Promoter IC25=10 uM; Antiulcer; Antiviral; Autotoxic; Cancer-Preventive; Cardioprotective; Chemopreventive; Cholagogue; Choleretic; Clastogenic; CNS-Active; CNS-Stimulant 1/6 Caffeine; Collagen-Sparing; Diuretic; Fungicide; Hepatoprotective; Histamine-Inhibitor; Hypoglycemic; Immunostimulant; Insectifuge; Interferonogenic; Juvabional; Larvistat; Leukotriene-Inhibitor; Lipoxygenase-Inhibitor IC23=5 mM; Metal-Chelator; NO-Genic; Ornithine-Decarboxylase-Inhibitor; Oviposition-Stimulant; Pesticide; Sunscreen; Sweetener; Vulnerary

CIS-EPOXYOCIMENE Leaf 800 - 5,700 ppm

No activity reported.

EO Leaf 2,500 - 17,000 ppm

No activity reported.

FAT Leaf 334,000 - 381,000 ppm

No activity reported.

FORMIC-ACID Plant:

Acaricide; Antiseptic; Antisyncopic; Astringent; Corrosive; Counterirritant; FLavor FEMA 500-2,500; Fungistat; Fungitoxic; Irritant; Pesticide; Preservative; Toxic

HYDROXYPELENOLIDE Plant:

No activity reported.

INULOBIOSE Plant:

No activity reported.

ISOABSINTHIN Plant:

No activity reported.

ISOQUERCITRIN Leaf:

ACE-Inhibitor ID50=300 ug/ml rat (24 hr.); Aldose-Reductase-Inhibitor; Antibacterial; Anticancer; Antielastase IC50=0.7 ug/ml; Antifeedant; Antiinflammatory; Antinociceptive; Antioxidant 1/4 quercetin IC50=9.0 uM; Antiradicular 1/4 quercetin; Antitumor; Antitumor-Promoter; Cancer-Preventive; Capillarigenic; Diaphoretic; Diuretic 10 ppm; Hypotensive; Insectiphile; Pesticide; TNF-alpha-Inhibitor; Topoisomerase-II-Inhibitor 550 ug/ml

ISORHAMNETIN-3-0-RHAMNOGLUCOSIDE Plant:

No activity reported.

ISORHAMNETIN-3-GLUCOSIDE Leaf:

Hepatoprotective

KETOPELENOLIDES Plant:

No activity reported.

LIRIORESINOL Plant:

No activity reported.

MATRISIN Plant:

No activity reported.

METHYL-3-(5-PROP-1-YNE-1YL-THIENYL-(2)-PROPIONATE Plant:

No activity reported.

NICOTINIC-ACID Plant:

Antichilblain 50 mg/3x/day; AntiCrohn's; Antidote (pesticides); Antischizophrenic; Antithyrotoxic; Choleretic; Hypocholesterolemic 1-6 g/man/day; Hypoglycemic; Insulinase-Inhibitor; Insulinotonic; Lipolytic

P-COUMARIC-ACID Plant:

Aldose-Reductase-Inhibitor 4 ug/ml (weak activity); Allelopathic; Antibacterial; Anticlastogen; Antifertility; Antihepatotoxic; Antileukemic IC50=25-56 ug/ml; Antinitrosaminic; Antioxidant 1/3 BHA IC24=30 ppm; Antiperoxidant IC50=>100 uM; Antiseptic; Antispasmodic; Antitumor; Cancer-Preventive; Chemopreventive; Choleretic; Cytotoxic; Diaphoretic?; Fungicide; Lipoxygenase-Inhibitor IC11=5 mM; Pesticide; Prostaglandigenic; Prostaglandin-Synthesis-Inhibitor; Tyrosinase-Inhibitor ID50=3,650 uM

P-HYDROXYPHENYLACETIC-ACID Plant:

No activity reported.

PALMITIC-ACID Plant:

5-Alpha-Reductase-Inhibitor; Antialopecic; Antiandrogenic; Antifibrinolytic; Antioxidant IC40=60; FLavor FEMA 1; Hemolytic; Hypercholesterolemic; Lubricant; Nematicide; Pesticide; Propecic; Soap

PATUELTIN-3-0-RHAMNOSIDE Leaf 16 - 32 ppm

No activity reported.

PATULETIN-3-0-GLUCOSIDE Leaf 16 - 32 ppm

No activity reported.

PHELLANDRENE Plant:

Hyperthermic; Irritant; Spasmogenic; Tumor-Promoter

PINENE Plant:

Allergenic; Antibacterial; Antiseptic; Antispasmodic; Convulsant; Enterocontractant; Expectorant; Fungicide; Herbicide IC50=30 mM; Perfumery; Pesticide; Spasmogenic

PIPECOLIC-ACID Plant:

Herbistat; Pesticide

PROTEIN Seed 258,000 - 334,000 ppm

No activity reported.

PROTOCATECHUIC-ACID Plant:

Allergenic; Alpha-Glucosidase-Inhibitor; Antiarrhythmic; Antiasthmatic; Antibacterial; Anticlastogen; Antihepatotoxic; Antiherpetic; Antiinflammatory; Antiischemic; AntiLegionella; Antileukemic; Antimelanogenic ID60=0.5 uM/ml; Antimutagenic; Antiophidic; Antioxidant 1/2 BHT 10 x alpha-tocopherol 2/3 quercetin; Antiperoxidant IC50=>100 uM IC75=200 ug/ml; Antiradicular; Antiseptic; Antispasmodic EC50=4.6-17 uM; Antitumor (Colon); Antitumor (Mouth); Antitumor (Skin); Antitussive; Antiviral; Apoptotic; Carcinogenic; Cardioprotective; Chemopreventive 100 ppm orl rat; Fungicide 500 ug/ml; Glutathione-Depleting; Hepatotoxic; Immunostimulant; Nephrotoxic; Pesticide; Phagocytotic; Prostaglandigenic; Secretogogue; Tyrosinase-Inhibitor ID60=0.5 uM/ml; Ubiquiot

QUEBRACHITOL Plant:

No activity reported.

QUERCITIN-3-0-BETA-D-GLUCOSIDE Plant:

No activity reported.

QUERCITIN-3-0-RHAMNOGLUCOSIDE Plant:

No activity reported.

RUTIN Plant:

5-HT-Inhibitor; Aldehyde-Oxidase-Inhibitor IC27-52=10 uM; Aldose-Reductase-Inhibitor 100 uM 4 ug/ml; Allelochemic; Antiaggregant ED50=33 nmol/kg iv; Antiallergic; Antiapoplectic; Antiatherogenic; Antiatherosclerotic; Antibacterial; Anticancer; Anticapillary-Fragility 20-100 mg orl man; Anticataract; Anticlastogen; Anticonvulsant; AntiCVI 270 mg/man/day; Antidementia; Antidermatitic; Antidiabetic; Antiedemic 270 mg/day orl man; Antierythemic; Antifeedant; Antiglaucomic 60 mg/day; Antihematuric; Antihemorrhoidal; Antihepatotoxic; Antiherpetic; Antihistaminic; Antihypertensive; Antiinflammatory 20 mg/kg; Antimalarial IC50=>100 ug/ml; Antimelanomic; Antimetastatic; Antimutagenic ID50=2-5 nM; Antinephritic; Antinociceptive; Antioxidant IC28=30 ppm IC50=120 uM IC54=10 uM; Antiperoxidant IC50=10-20 uM; Antiplatelet; Antiproliferant 50-75 uM/l; Antiprotozoal; Antipurpuric; Antiradicular 9 x quercetin; Antispasmodic; Antisunburn; Antithrombogenic EC50=500 nM; Antithyroid IC50=68 uM; Antitrypanosomic 100 mg/kg; Antitumor; Antitumor-Promoter; Antiulcer; Antivaricose; Antiviral; Apoptotic 75 uM/l; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Capillariprotective; Catabolic; Chemopreventive; Cytoprotective IC50=3 uM; Estrogenic?; Hemostat; Hepatomagenic 20,000 ppm (diet) rat; Hepatoprotective 20 mg/kg rat; Hypocholesterolemic; Hypotensive; Immunomodulator; Insecticide; Insectiphile; Juvabional; Larvistat IC95=4,000-8,000 ppm diet; Lipoxygenase-Inhibitor IC75=2.5 mM; Mutagenic; Myoprotective; Myorelaxant; Oviposition-Stimulant; PAF-Inhibitor; Pesticide; Protisticide; Radioprotective; Sunscreen; Topoisomerase-II-Inhibitor IC50=1 ug/ml; Vasodilator; Vasopressor

SABINENE Plant:

Antibacterial; Antihelicobacter; Antiseptic; Antiulcer; Perfumery

SALICYLIC-ACID Plant:

Aldose-Reductase-Inhibitor 724.6 uM; Analgesic; Antiarthritic; Antibacterial; Antidandruff; Antidermatotic; Antieczemic; Antiichthyosic; Antiinflammatory; Antineuralgic; Antioncychomycotic; Antioxidant; Antiperiodic; Antipodagric; Antipsoriac; Antipyretic; Antirheumatic; Antiseborrheic; Antiseptic; Antitumor; Antitympanitic; Cancer-Preventive; Comedolytic; COX-2-Inhibitor; Cyclooxygenase-Inhibitor; Dermatitigenic; Fungicide MIC 1,000 ug/ml; Hypoglycemic; Insectifuge; Keratolytic; Pesticide; Thermogenic 130 ppm; Tineacide; Ulcerogenic

SPINACETIN-3-0-GLUCOSIDE Leaf 80 ppm;

No activity reported.

SPINACETIN-3-0-RHAMNOGLUCOSIDE Leaf 16 - 32 ppm

No activity reported.

SYRINGIC-ACID Plant:

Allelopathic; Antioxidant 1/3 BHA IC39=30 ppm; Antiperoxidant IC10-70=100-200 ug/ml; Antiradicular EC50=5.5-8 ug/ml; Ubiquiot

TANNIN Leaf 40,000 - 77,000 ppm

Anthelmintic; Antibacterial; Anticancer; Anticariogenic; Antidiarrheic; Antidysenteric; Antihepatotoxic; AntiHIV; Antihypertensive; Antilipolytic; Antimutagenic; Antinephritic; Antiophidic; Antioxidant 1/3 quercetin IC50=1.44 ug/ml; Antiradicular 1/3 quercetin 500 mg/kg/day orl mus; Antirenitic; Antitumor; Antitumor-Promoter; Antiulcer; Antiviral; Cancer-Preventive; Carcinogenic; Chelator; Cyclooxygenase-Inhibitor; Glucosyl-Transferase-Inhibitor; Hepatoprotective; Immunosuppressant; Lipoxygenase-Inhibitor; MAO-Inhibitor; Ornithine-Decarboxylase-Inhibitor; Pesticide; Psychotropic; Xanthine-Oxidase-Inhibitor

THUJYL-ALCOHOL Plant:

No activity reported.

THUJYL-ISOVALERATE Plant:

No activity reported.

THUJYL-PALMITATE Plant:

No activity reported.

TRANS-DEHYDROMATRICARIA-ESTER Root:

Nematicide; Pesticide

TRANS-EPOXYOCIMENE Leaf 800 - 5,700 ppm

No activity reported.

TRANS-SAQBINYL-ACETATE Plant:

No activity reported.

TRANS-SPIROKETALENOL Root:

No activity reported.

VANILLIC-ACID Plant:

Aldose-Reductase-Inhibitor 100 uM/l; Allelopathic; Anthelmintic; Antibacterial 1.5-15 mg/ml; Anticancer; Antifatigue; Antiinflammatory; Antileukemic IC50=25-56 ug/ml; Antioxidant 1/3 BHA IC21=30 ppm; Antiperoxidant IC15-65=100-200 ug/ml; Antiradicular 7 x quercetin; Antiseptic; Antisickling; Antitumor; Antitumor-Promoter; Ascaricide; Cancer-Preventive; Choleretic; Fungicide; Immunosuppressant; Laxative; Pesticide; Ubiquiot

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ppm = parts per million
tr = trace